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Zhong Y, Li SH, Liu SM, Szmitko PE, He XQ, Fedak PW, Verma S: C-Reactive protein upregulates receptor for advanced glycation end products expression in human endothelial cells. Hypertension. 2006 Sep;48(3):504-11. Epub 2006 Jul 17.
The receptor for advanced glycation end products (RAGE) may play an important role in inflammatory processes and endothelial activation, likely to accelerate the processes of coronary atherosclerotic development, especially in diabetic patients.
Human saphenous vein endothelial cells were incubated with human recombinant CRP, free of sodium azide and endotoxin. |
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