Protein Information

Name cytoplasmic proteins
Synonyms BLZF 1; BLZF1; Basic leucine zipper nuclear factor 1; Basic leucine zipper nuclear factor 1 (JEM 1); Cytoplasmic protein; GOLGIN 45; JEM 1; JEM 1s…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
15925899 Horne I, Williams M, Sutherland TD, Russell RJ, Oakeshott JG: A Brevibacillus choshinensis system that secretes cytoplasmic proteins. . J Mol Microbiol Biotechnol. 2004;8(2):81-90.

The inhibitors carbonyl cyanide m-chlorophenyl hydrazine and sodium azide were used to confirm that secretion was occurring via the TAT secretion pathway.
2(0,0,0,2) Details
8788121 Oguri-Hyakumachi N, Takahashi S, Nakagawa T, Kikuchi K: Selective depletion of cyclin-dependent kinases is associated with Fas-mediated apoptosis in human leukemia T-cell lines. Int J Immunopharmacol. 1995 Nov;17(11):913-21.

In the present study, we examined the changes in cytoplasmic proteins of the Fas-sensitive and Fas-resistant cells after stimulation with anti-Fas antibody, 2D1.
This observation seemed specific to Fas-mediated apoptosis, because calcium ionophore A23187 or sodium azide failed to repress the expression of cdks.
1(0,0,0,1) Details
9398078 Kay L, Li Z, Mericskay M, Olivares J, Tranqui L, Fontaine E, Tiivel T, Sikk P, Kaambre T, Samuel JL, Rappaport L, Usson Y, Leverve X, Paulin D, Saks VA: Study of regulation of mitochondrial respiration in vivo. Biochim Biophys Acta. 1997 Nov 10;1322(1):41-59.


However, short treatment of fibers with trypsin decreased this constant value to 40-70 microM, confirming the earlier proposition that mitochondrial sensitivity to ADP in vivo is controlled by some cytoplasmic protein.
1(0,0,0,1) Details
8655479 Jander G, Cronan JE Jr, Beckwith J: Biotinylation in vivo as a sensitive indicator of protein secretion and membrane protein insertion. J Bacteriol. 1996 Jun;178(11):3049-58.

Escherichia coli biotin ligase is a cytoplasmic protein which specifically biotinylates the biotin-accepting domains from a variety of organisms.
Inhibition of SecA with sodium azide and mutations in SecB, SecD, and SecF, all of which slow down protein secretion, result in biotinylation of PSBT.
1(0,0,0,1) Details
12392157 Woon ST, Baguley BC, Palmer BD, Fraser JD, Ching LM: Uptake of the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and activation of NF-kappaB in human tumor cell lines. Oncol Res. 2002;13(2):95-101.

All lines accumulated [3H] DMXAA, and uptake by ECV304 cells was rapid, pH dependent (greater uptake at pH 6.5), similar at 4 degrees C and 37 degrees C, and unaffected by the addition of 5 mM sodium azide.
The uptake ratio was 4.5-fold at a low drug concentration (4 microM) and decreased significantly (P < 0.01) to 4.0 as the external drug concentration was increased to 0.7 mM, providing evidence of saturability. [3H] DMXAA interacted weakly with isolated cytoplasmic proteins, as measured by equilibrium dialysis, providing a basis for the observed cellular uptake.
1(0,0,0,1) Details