Protein Information

Name MCT4
Synonyms MCT 4; MCT4; Monocarboxylate transporter 4; MCT 5; MCT5; Monocarboxylate transporter 5; SLC16A4; Solute carrier family 16 member 4…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
19505879 Schneiderhan W, Scheler M, Holzmann KH, Marx M, Gschwend JE, Bucholz M, Gress TM, Seufferlein T, Adler G, Oswald F: CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. Gut. 2009 Oct;58(10):1391-8. Epub 2009 Jun 7.

Further induction of lactate production by sodium azide in MiaPaCa2 cells increased MCT1 as well as MCT4 expression.
35(0,1,1,5) Details
15804185 Majumdar S, Gunda S, Pal D, Mitra AK: Functional activity of a monocarboxylate transporter, MCT1, in the human retinal pigmented epithelium cell line, ARPE-19. Mol Pharm. 2005 Mar-Apr;2(2):109-17.

Uptake was significantly decreased in the presence of sodium azide, ouabain, p-chloromercuribenzoic acid (pCMBA), N-ethylmaleamide, dithiothreitol, and p-chloromercuribenzene sulfonate (pCMBS).
ELISA indicated the expression of only MCT1, MCT4, and MCT8 isoforms by ARPE-19 cells.
1(0,0,0,1) Details