Protein Information

Name matrix metalloproteinase 1
Synonyms MMP 14; Matrix metalloproteinase 1; MMP X1; MMP14; MT MMP 1; MT1 MMP; MT1MMP; MTMMP 1…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
12542540 Karrer S, Bosserhoff AK, Weiderer P, Landthaler M, Szeimies RM: Influence of 5-aminolevulinic acid and red light on collagen metabolism of human dermal fibroblasts. J Invest Dermatol. 2003 Feb;120(2):325-31.

Addition of nontoxic concentrations of sodium azide, a singlet-oxygen quencher, significantly inhibited induction of matrix metalloproteinase 1 by 5-aminolevulinic acid and light.
85(1,1,1,5) Details
7829875 Wlaschek M, Briviba K, Stricklin GP, Sies H, Scharffetter-Kochanek K: Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase. J Invest Dermatol. 1995 Feb;104(2):194-8.

We studied the role of singlet oxygen in the downstream signaling of the complex UV response leading to the induction of matrix-metalloproteinase-1 (interstitial collagenase/MMP-1).
In contrast, sodium azide, a potent quencher of singlet oxygen, almost totally abrogated the induction of collagenase after exposure of fibroblasts to NDPO2 or to UVA irradiation.
1(0,0,0,1) Details