Protein Information

Name ERK2
Synonyms ERK; P40; ERK 2; ERK2; ERT 1; ERT1; Extracellular signal regulated kinase 2; MAP kinase 2…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
9360968 Yu R, Tan TH, Kong AN: Butylated hydroxyanisole and its metabolite tert-butylhydroquinone differentially regulate mitogen-activated protein kinases. J Biol Chem. 1997 Nov 14;272(46):28962-70.

Furthermore, BHA and tBHQ activation of ERK2 was strongly inhibited by ascorbic acid and a peroxidase inhibitor, sodium azide, suggesting the potential role of phenoxyl radicals and/or their derivatives.
86(1,1,1,6) Details
12945585 Le Panse R, Dubertret L, Coulomb B: p38 mitogen-activated protein kinase activation by ultraviolet A radiation in human dermal fibroblasts. Photochem Photobiol. 2003 Aug;78(2):168-74.


L-Histidine and sodium azide had an inhibitory effect on UVA activation of p38 MAPK, pointing to a role of singlet oxygen in transduction of the UVA effect.
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11547566 Nakano H, Gasparro FP, Uitto J: UVA-340 as energy source, mimicking natural sunlight, activates the transcription factor AP-1 in cultured fibroblasts: evidence for involvement of protein kinase-C. Photochem Photobiol. 2001 Aug;74(2):274-82.


Free radical quenchers, sodium azide and N-acetylcysteine, did not affect the AP-1 binding activity.
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17384288 Siniscalchi A, Cavallini S, Marino S, Falzarano S, Franceschetti L, Selvatici R: Effects of chemical ischemia on cerebral cortex slices: focus on mitogen-activated protein kinase cascade. Ann N Y Acad Sci. 2006 Dec;1090:445-54.


In superfused, electrically stimulated rat cerebral cortex slices, chemical ischemia (CI) was induced by a 5-min treatment with the mitochondrial toxin, sodium azide (10 mM), combined with the glycolysis blocker, 2-deoxyglucose (2 mM).
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