| Name | GLUT1 |
|---|---|
| Synonyms | Erythrocyte/hepatoma glucose transporter; GLUT; GLUT 1; GLUT1; Glucose transporter 1; HepG2 glucose transporter; SLC2A1; Glucose transporter 1s… |
| Name | sodium azide |
|---|---|
| CAS | sodium azide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14578187 | Heilig C, Brosius F, Siu B, Concepcion L, Mortensen R, Heilig K, Zhu M, Weldon R, Wu G, Conner D: Implications of transporter protein type 1 (GLUT1)-haplodeficiency in embryonic stem cells for their survival in response to hypoxic stress. Am J Pathol. 2003 Nov;163(5):1873-85. |
9(0,0,0,9) | Details |
| 9788740 | Behrooz A, Ismail-Beigi F: Induction of GLUT1 mRNA in response to azide and inhibition of protein synthesis. Mol Cell Biochem. 1998 Oct;187(1-2):33-40. |
6(0,0,0,6) | Details |
| 10572068 | Ouiddir A, Planes C, Fernandes I, VanHesse A, Clerici C: Hypoxia upregulates activity and expression of the transporter GLUT1 in alveolar epithelial cells. Am J Respir Cell Mol Biol. 1999 Dec;21(6):710-8. |
5(0,0,0,5) | Details |
| 9685425 | Hresko RC, Heimberg H, Chi MM, Mueckler M: Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP. J Biol Chem. 1998 Aug 7;273(32):20658-68. Subcellular fractionation experiments demonstrated that reduction in insulin-stimulated 2-deoxyglucose uptake by was due to an inhibition of translocation of both Glut 1 and Glut 4 from the low density microsomes (LDM) to the plasma membrane. |
2(0,0,0,2) | Details |
| 11171597 | Kang J, Heart E, Sung CK: Effects of cellular ATP depletion on transport and insulin signaling in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab. 2001 Mar;280(3):E428-35. To study the role of ATP depletion in insulin resistance, we employed sodium azide (NaN3) and dinitrophenol (DNP), which affect mitochondrial oxidative phosphorylation, to achieve a similar 15% ATP depletion. Unlike NaN3 and DNP markedly increased basal transport, and the increased basal transport was associated with increased GLUT-1 content in the plasma membrane without changes in total GLUT-1 content. |
1(0,0,0,1) | Details |
| 17957036 | Brown AE, Elstner M, Yeaman SJ, Turnbull DM, Walker M: Does impaired mitochondrial function affect insulin signaling and action in cultured human skeletal muscle cells?. Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E97-102. Epub 2007 Oct 23. GLUT1 mRNA expression remained unchanged, whereas GLUT4 mRNA expression increased following azide treatment. To address this, a model of impaired cellular respiratory function was established by incubating human skeletal muscle cell cultures with the mitochondrial inhibitor sodium azide and examining the effects on insulin action. |
1(0,0,0,1) | Details |
| 9382751 | Speert DP, Wong SY, Macdonald M, Sargeant R: Modulation of macrophage function for defence of the lung against Pseudomonas aeruginosa. Behring Inst Mitt. 1997 Feb;(98):274-82. Treatment of freshly explanted pulmonary alveolar macrophages with sodium azide (to poison oxidative respiration) dramatically enhances both transport and -dependent phagocytosis of P. aeruginosa. We have shown that phagocytosis of unopsonized P. aeruginosa depends upon facilitated transport of into macrophages via the GLUT1 isoform. |
1(0,0,0,1) | Details |