| Name | Kir6.1 |
|---|---|
| Synonyms | ATP sensitive inward rectifier potassium channel 8; Inwardly rectifier K(+) channel Kir6.1; Inwardly rectifier K+ channel Kir6.1; Inwardly rectifying potassium channel Kir6.1; KCNJ 8; KCNJ8; KIR6.1; uKATP 1… |
| Name | sodium azide |
|---|---|
| CAS | sodium azide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10516647 | Surah-Narwal S, Xu SZ, McHugh D, McDonald RL, Hough E, Cheong A, Partridge C, Sivaprasadarao A, Beech DJ: Block of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A. Br J Pharmacol. 1999 Oct;128(3):667-72. Metabolic poisoning of Xenopus laevis oocytes with sodium azide and application of the K+ channel opener drug diazoxide induced K+ channel currents in oocytes co-injected with cRNA for hKir6.1 and hamster sulphonylurea receptor (SUR1), but not in oocytes injected with water or cRNA for hKir6.1 or SUR1 alone. 3. |
2(0,0,0,2) | Details |
| 10050011 | Lee K, Dixon AK, Richardson PJ, Pinnock RD: -receptive neurones in the rat ventromedial hypothalamus express KATP channels composed of Kir6.1 and SUR1 subunits. J Physiol. 1999 Mar 1;515 ( Pt 2):439-52. In cell-attached recordings, removal of extracellular or metabolic inhibition with sodium azide reduced the firing rate of a subpopulation of cells through the activation of a 65 pS channel that was blocked by the sulphonylureas and glibenclamide. 2. |
1(0,0,0,1) | Details |
| 9705995 | Lee K, Dixon AK, Freeman TC, Richardson PJ: Identification of an ATP-sensitive potassium channel current in rat striatal cholinergic interneurones. J Physiol. 1998 Jul 15;510 ( Pt 2):441-53. It is concluded that cholinergic interneurones within the rat striatum exhibit a KATP channel current and that this channel is formed from Kir6.1 and SUR1 subunits. Using permeabilized patch recordings, neurones were shown to hyperpolarize in response to deprivation or metabolic poisoning with sodium azide (NaN3). |
1(0,0,0,1) | Details |