| Name | Ha ras |
|---|---|
| Synonyms | C H RAS; Transforming protein p21; N ras; HRAS1; HRASP; C H ras 1 protein N terminal fragment (37 AA); C has/bas p21 protein; C ras Ki 2 protein… |
| Name | sodium azide |
|---|---|
| CAS | sodium azide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12184785 | Oikawa S, Hiraku Y, Fujiwara T, Saito I, Kawanishi S: Site-specific hydroxylation at polyguanosine in double-stranded DNA by (II) in the presence of SH compounds: comparison with singlet -induced DNA damage. Chem Res Toxicol. 2002 Aug;15(8):1017-22. In the presence of model endogenous SH compounds, (DTT), 1,4-dithio- and dithioerythritol, Ni (II) induced damage to (32) P-5'-end-labeled DNA fragments obtained from the human c-Ha-ras-1 protooncogene and the p53 tumor suppressor gene. Sodium azide, a potent and relatively specific scavenger of (1) O (2), inhibited DNA damage by Ni (II) in the presence of DTT, whereas the sequence specificity of DNA damage was different from that obtained by (1) O (2) generating agent. |
1(0,0,0,1) | Details |
| 11068871 | Hiraku Y, Kawanishi S: Distinct mechanisms of -specific DNA photodamage induced by nalidixic acid and fluoroquinolone antibacterials. Arch Biochem Biophys. 2000 Oct 15;382(2):211-8. We investigated the mechanisms of DNA damage by UVA radiation (365 nm) plus fluoroquinolone antibacterials using 32P-labeled DNA fragments obtained from the human c-Ha-ras-1 proto-oncogene and the p53 tumor suppressor gene. LFLX-induced DNA photodamage was inhibited by sodium azide and enhanced in D2O, suggesting that singlet plays the key role in the DNA damage. |
1(0,0,0,1) | Details |
| 17384288 | Siniscalchi A, Cavallini S, Marino S, Falzarano S, Franceschetti L, Selvatici R: Effects of chemical ischemia on cerebral cortex slices: focus on mitogen-activated protein kinase cascade. Ann N Y Acad Sci. 2006 Dec;1090:445-54. In superfused, electrically stimulated rat cerebral cortex slices, chemical ischemia (CI) was induced by a 5-min treatment with the mitochondrial toxin, sodium azide (10 mM), combined with the glycolysis blocker, 2-deoxyglucose (2 mM). Western blot analysis of p21Ras, extracellular signal-regulated protein kinases (ERK) 1/2 (p44/42), phospho-ERK1/2, mitogen-activated protein kinase (MAPK)-p38, phospho-p38, stress-activated protein kinases/c-Jun NH2-terminal protein kinases (SAPK/JNK), phospho-SAPK/JNK was carried out. |
2(0,0,0,2) | Details |