Protein Information

Name CYP3A4
Synonyms CP33; CYP3; HLP; CYP3A; CP34; CYP 3A4; CYP 3; CYP3A3…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
11236840 Salmela KS, Tsyrlov IB, Lieber CS: Azide inhibits human cytochrome P -4502E1, 1A2, and 3A4. Alcohol Clin Exp Res. 2001 Feb;25(2):253-60.

CONCLUSIONS: Sodium azide at a concentration as low as 0.1 mM inhibited ethanol oxidation by CYP1A2 and CYP3A4.
116(1,2,2,6) Details
17520814 Tian L, Yang XW, Wang Y, Xu W: [Characteristics of uptake, transport and efflux of Z- and E-ajoenes in Caco-2 cell monolayers in vitro]. Yao Xue Xue Bao. 2007 Jan;42(1):87-92.

The metabolism of Z- and E-ajoenes in Caco-2 cell monolayers can be partially inhibited by vitamin C as an anti-oxidant, metyrapone as an inhibitor to subtype CYP3A of cytochrome P450 drug metabolism enzymes, and sodium azide as an inhibitor to ATP production.
81(1,1,1,1) Details
11389877 He K, Woolf TF, Kindt EK, Fielder AE, Talaat RE: Troglitazone quinone formation catalyzed by human and rat CYP3A: an atypical CYP oxidation reaction. Biochem Pharmacol. 2001 Jul 15;62(2):191-8.

2(0,0,0,2) Details