| Name | CYP2E1 |
|---|---|
| Synonyms | CPE 1; Flavoprotein linked monooxygenase; Xenobiotic monooxygenase; Microsomal monooxygenase; CPE1; CYP2E; CYP2E1; CYP2E1 protein… |
| Name | sodium azide |
|---|---|
| CAS | sodium azide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16930212 | Zimatkin SM, Pronko SP, Vasiliou V, Gonzalez FJ, Deitrich RA: Enzymatic mechanisms of oxidation in the brain. . Alcohol Clin Exp Res. 2006 Sep;30(9):1500-5. RESULTS: The catalase inhibitors sodium azide (5 mM) and aminotriazole (5 mM) as well as CYP2E1 inhibitors diallyl sulfide (2 mM) and beta-phenethyl isothiocyanate (0.1 mM) lowered significantly the accumulation of the -derived AC and in brain homogenates. |
35(0,1,1,5) | Details |
| 11236840 | Salmela KS, Tsyrlov IB, Lieber CS: Azide inhibits human cytochrome P -4502E1, 1A2, and 3A4. Alcohol Clin Exp Res. 2001 Feb;25(2):253-60. BACKGROUND: Recently, we showed that, in addition to cytochrome P-4502E1 (CYP2E1), CYP1A2 and CYP3A4 also contribute to the microsomal oxidizing system (MEOS). When MEOS activity is measured, sodium azide commonly is used to block the contaminating catalase. |
5(0,0,0,5) | Details |
| 8625450 | Barcelo S, Gardiner JM, Gescher A, Chipman JK: CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent Carcinogenesis. 1996 Feb;17(2):277-82. was unable to inhibit mutagenicity of sodium azide (5 micrograms/plate), a direct acting mutagen, in the Salmonella assay. |
4(0,0,0,4) | Details |
| 17267090 | Zodl B, Schmid D, Wassler G, Gundacker C, Leibetseder V, Thalhammer T, Ekmekcioglu C: Intestinal transport and metabolism of acrylamide. Toxicology. 2007 Mar 22;232(1-2):99-108. Epub 2006 Dec 22. As the intestinal mechanisms of acrylamide absorption are poorly investigated we studied the transport of acrylamide in differentiated Caco-2 cells and its effects on biotransformation enzymes (CYP2E1 and glutathione S-transferase) and levels. Predominantly, basal to apical transport was decreased when energy metabolism of the cells was inhibited by application of sodium azide and 2-deoxy- |
1(0,0,0,1) | Details |