Protein Information

Name PK1
Synonyms Black mamba toxin related protein; PRK 1; PRK1; EG VEGF; EGVEGF; Endocrine gland derived vascular endothelial growth factor; Mambakine; PK1…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
8786975 Takakura Y, Morita T, Fujikawa M, Hayashi M, Sezaki H, Hashida M, Borchardt RT: Characterization of LLC-PK1 kidney epithelial cells as an in vitro model for studying renal tubular reabsorption of protein drugs. Pharm Res. 1995 Dec;12(12):1968-72.

The association of STI decreased with increases in medium pH from 5.4 to 8.4 and was inhibited significantly by 2,4-dinitrophenol, sodium azide, cytochalasin B, and colchicine, suggesting that the cellular association involved endocytosis.
6(0,0,0,6) Details
9512098 Takakura Y, Oka Y, Hashida M: Cellular uptake properties of oligonucleotides in LLC-PK1 renal epithelial cells. Antisense Nucleic Acid Drug Dev. 1998 Feb;8(1):67-73.

The association was inhibited significantly by sodium azide and chloroquine, suggesting that an energy-dependent endocytotic process was involved.
4(0,0,0,4) Details
11724763 Florea BI, van der Sandt IC, Schrier SM, Kooiman K, Deryckere K, de Boer AG, Junginger HE, Borchard G: Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3). Br J Pharmacol. 2001 Dec;134(7):1555-63.

Transepithelial transport of flunisolide was studied in reconstituted cell monolayers of Calu-3, LLC-PK1 and the MDR1-P-glycoprotein transfected LLC-MDR1 cells. 2.
Non-specific inhibition of cellular metabolism at low temperature (4 degrees C) or by 2-deoxy-D-glucose (2-d-glu) and sodium azide (NaN (3)) abolished the polarized transport.
1(0,0,0,1) Details