Protein Information

Name phosphodiesterase
Synonyms CAMP specific phosphodiesterase variant PDE4A 10; CAMP specific phosphodiesterase variant TM3; CAMP specific phosphodiesterase; Cyclic AMP phosphodiesterase PDE4A11; Cyclic AMP specific phosphodiesterase HSPDE4A10; DPDE 2; DPDE2; PDE 4…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
16421009 Furstenau CR, Trentin Dda S, Barreto-Chaves ML, Sarkis JJ: Ecto-nucleotide pyrophosphatase/phosphodiesterase as part of a multiple system for nucleotide hydrolysis by platelets from rats: kinetic characterization and biochemical properties. Platelets. 2006 Mar;17(2):84-91.

Besides, 5.0, 10 and 20 mM sodium azide just inhibited ATP and ADP hydrolysis.
2(0,0,0,2) Details
10455294 Shahidullah M, Wilson WS: Atriopeptin, sodium azide and cyclic GMP reduce secretion of aqueous humour and inhibit intracellular calcium release in bovine cultured ciliary epithelium. Br J Pharmacol. 1999 Jul;127(6):1438-46.

This response showed concentration-dependent inhibition by atriopeptin, azide or 8-bromo cyclic GMP, and this inhibition of the rapid (peak) Ca2+ increase was enhanced by zaprinast (100 microM; phosphodiesterase inhibitor).
1(0,0,0,1) Details
17786543 Rucker B, Almeida ME, Libermann TA, Zerbini LF, Wink MR, Sarkis JJ: Biochemical characterization of ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP, E.C. 3.1.4.1) from rat heart left ventricle. Mol Cell Biochem. 2007 Dec;306(1-2):247-54. Epub 2007 Sep 5.

Sodium azide (10 and 20 mM) and gadolinium chloride (0.3 and 0.5 mM), E-NTPases inhibitors, had no effects on p-Nph-5'-TMP hydrolysis.
1(0,0,0,1) Details
12218047 Jongbloed JD, Antelmann H, Hecker M, Nijland R, Bron S, Airaksinen U, Pries F, Quax WJ, van Dijl JM, Braun PG: Selective contribution of the twin-arginine translocation pathway to protein secretion in Bacillus subtilis. J Biol Chem. 2002 Nov 15;277(46):44068-78. Epub 2002 Sep 5.

In fact, only the phosphodiesterase PhoD was shown to be secreted in a strictly Tat-dependent manner.
Sodium azide-inhibition of SecA strongly affected the extracellular appearance of de novo synthesized proteins, including the lipase LipA and two other proteins with predicted RR/KR-signal peptides.
1(0,0,0,1) Details