Protein Information

Name pyrophosphatase
Synonyms Cytosolic inorganic pyrophosphatase; IOPPP; Inorganic pyrophosphatase; Inorganic pyrophosphatase 1; PP; PP1; PPA 1; PPA1…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
19961421 Sen SS, Bhuyan NR, Lakshman K, Roy AK, Chakraborty B, Bera T: Membrane bound pyrophosphatase and P-type adenosine triphosphatase of Leishmania donovani as possible chemotherapeutic targets: similarities and differences in inhibitor sensitivities. Biochemistry. 2009 Dec;74(12):1382-7.

ATPase activity was stimulated by K+ and verapamil, inhibited by DCCD, PCMBS, NEM, sodium azide, sodium orthovanadate, and quercetin, and was unaffected by PAO.
6(0,0,0,6) Details
16421009 Furstenau CR, Trentin Dda S, Barreto-Chaves ML, Sarkis JJ: Ecto-nucleotide pyrophosphatase/phosphodiesterase as part of a multiple system for nucleotide hydrolysis by platelets from rats: kinetic characterization and biochemical properties. Platelets. 2006 Mar;17(2):84-91.

Besides, 5.0, 10 and 20 mM sodium azide just inhibited ATP and ADP hydrolysis.
2(0,0,0,2) Details
17786543 Rucker B, Almeida ME, Libermann TA, Zerbini LF, Wink MR, Sarkis JJ: Biochemical characterization of ecto-nucleotide pyrophosphatase/phosphodiesterase (E-NPP, E.C. 3.1.4.1) from rat heart left ventricle. Mol Cell Biochem. 2007 Dec;306(1-2):247-54. Epub 2007 Sep 5.

Sodium azide (10 and 20 mM) and gadolinium chloride (0.3 and 0.5 mM), E-NTPases inhibitors, had no effects on p-Nph-5'-TMP hydrolysis.
1(0,0,0,1) Details