| Name | NTPDase 1 |
|---|---|
| Synonyms | APYRASE; ATPDase; CD39; CD39 antigen; ENTPD 1; ENTPD1; ENTPD1 protein; Ecto ATP diphosphohydrolase… |
| Name | sodium azide |
|---|---|
| CAS | sodium azide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15652174 | Leal DB, Streher CA, Neu TN, Bittencourt FP, Leal CA, da Silva JE, Morsch VM, Schetinger MR: Characterization of NTPDase (NTPDase1; ecto-apyrase; ecto-diphosphohydrolase; CD39; EC 3.6.1.5) activity in human lymphocytes. Biochim Biophys Acta. 2005 Jan 18;1721(1-3):9-15. Epub 2004 Oct 6. Human lymphocytes contain NTPDase (NTPDase-1; ecto-apyrase; ecto-diphosphohydrolase; CD39; EC 3.6.1.5), a cation-dependent enzyme that hydrolyzes ATP and ADP and also other di- and nucleosides, acting at an optimum pH of 8.0. A significant inhibition of ATP and ADP hydrolysis (P <0.05) was observed in the presence of 20 mM sodium azide. |
1(0,0,0,1) | Details |
| 18201730 | Rucker B, Almeida ME, Libermann TA, Zerbini LF, Wink MR, Sarkis JJ: E-NTPDases and ecto-5'-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings. Life Sci. 2008 Feb 27;82(9-10):477-86. Epub 2008 Jan 16. RT-PCR analysis from left ventricle tissue demonstrate different levels of expression of Entpd1 (Cd39), Entpd2 (Cd39L1), Entpd3 (Cd39L3), Entpd5 (Cd39L4) Entpd6, (Cd39L2) and 5'-NT/CD73. Oligomycin (2 microg/mL) and sodium azide (0.1 mM), both mitochondrial ATPase inhibitors, inhibit only the ATP hydrolysis. |
1(0,0,0,1) | Details |
| 12637029 | Demenis MA, Furriel RP, Leone FA: Characterization of an ectonucleoside triphosphate diphosphohydrolase 1 activity in alkaline phosphatase-depleted rat osseous plate membranes: possible functional involvement in the calcification process. Biochim Biophys Acta. 2003 Mar 21;1646(1-2):216-25. However, suramin and sodium azide were effective inhibitors of ATP and ADP hydrolysis. |
3(0,0,0,3) | Details |
| 10510290 | Benrezzak O, Grondin G, Sevigny J, Gendron FP, Rousseau E, D'Orleans-Juste P, Beaudoin AR: Identification and immunolocalization of two isoforms of ATP-diphosphohydrolase (ATPDase) in the pig immune system. Arch Biochem Biophys. 1999 Oct 15;370(2):314-22. The parallel decrease in ATPase and ADPase activities, in the presence of sodium azide, indicated that an ATP diphosphohydrolase (ATPDase) was responsible for these activities. Identity of ATPDase was confirmed by electrophoretograms of the particulate fractions and Western immunoblots, with an antibody that recognizes ATPDases from different sources. |
1(0,0,0,1) | Details |
| 15979908 | Savegnago L, Nogueira CW, Fachinetto R, Rocha JB: Characterization of ATP and ADP hydrolysis activity in rat gastric mucosa. . Cell Biol Int. 2005 Jul;29(7):559-66. Sodium azide (0.03-30 mM), at high concentrations (> 0.1 mM), caused a parallel hydrolysis inhibition of ATP and ADP. |
0(0,0,0,0) | Details |
| 10231536 | Smith TM, Lewis Carl SA, Kirley TL: Mutagenesis of two conserved residues of the E-type ATPases: inactivation and conversion of an ecto-apyrase to an ecto-NTPase. Biochemistry. 1999 May 4;38(18):5849-57. In addition, the double mutant is substantially less sensitive to inhibition by azide, a more potent inhibitor of ecto-apyrases than ecto-ATPases. |
1(0,0,0,1) | Details |
| 19922813 | Rosemberg DB, Rico EP, Langoni AS, Spinelli JT, Pereira TC, Dias RD, Souza DO, Bonan CD, Bogo MR: NTPDase family in zebrafish: Nucleotide hydrolysis, molecular identification and gene expression profiles in brain, liver and heart. Comp Biochem Physiol B Biochem Mol Biol. 2010 Mar;155(3):230-40. Epub 2009 Nov 14. Sodium azide (20mM), ARL 67156 (300 microM) and Suramin (300 microM) differently altered the nucleotide hydrolysis in zebrafish tissues, suggesting the contribution of distinct NTPDase activities. RT-PCR experiments revealed the existence of a distinct relative entpd1-6 and entpd8 expression profile in brain, liver, and heart. |
1(0,0,0,1) | Details |