Protein Information

Name CD147
Synonyms 5F7; BSG; Basigin; Basigin precursor; CD147; CD147 antigen; Collagenase stimulatory factor; EMMPRIN…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
10233694 Kasinrerk W, Tokrasinwit N, Phunpae P: CD147 monoclonal antibodies induce homotypic cell aggregation of monocytic cell line U937 via LFA-1/ICAM-1 pathway. Immunology. 1999 Feb;96(2):184-92.

The U937 cell aggregation induced by CD147 mAb was also inhibited by ethylenediamine tetra-acetic acid (EDTA), sodium azide and when incubated at 4 degrees.
88(1,1,1,8) Details
18761711 Maekawa F, Minehira K, Kadomatsu K, Pellerin L: Basal and stimulated lactate fluxes in primary cultures of astrocytes are differentially controlled by distinct proteins. J Neurochem. 2008 Nov;107(3):789-98.

In contrast, basigin appears to critically regulate the enhancement of lactate release caused by glutamate (or sodium azide) but via an effect on another unidentified transporter at least present in astrocytes in vitro.
34(0,1,1,4) Details
19505879 Schneiderhan W, Scheler M, Holzmann KH, Marx M, Gschwend JE, Bucholz M, Gress TM, Seufferlein T, Adler G, Oswald F: CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models. Gut. 2009 Oct;58(10):1391-8. Epub 2009 Jun 7.

Further induction of lactate production by sodium azide in MiaPaCa2 cells increased MCT1 as well as MCT4 expression.
8(0,0,0,8) Details