| Name | caspase (protein family or complex) |
|---|---|
| Synonyms | caspase; caspases |
| Name | sodium azide |
|---|---|
| CAS | sodium azide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12954857 | Garnier P, Ying W, Swanson RA: Ischemic preconditioning by caspase cleavage of poly (ADP- polymerase-1. J Neurosci. 2003 Sep 3;23(22):7967-73. |
4(0,0,0,4) | Details |
| 10764744 | Bai J, Cederbaum AI: Overexpression of catalase in the mitochondrial or cytosolic compartment increases sensitivity of HepG2 cells to tumor necrosis factor-alpha-induced apoptosis. J Biol Chem. 2000 Jun 23;275(25):19241-9. Sodium azide, an inhibitor of catalase, reduced the increased sensitivity of mC5 and C33 cells to TNF-alpha to the level of toxicity found with control Hp cells. A pan-caspase inhibitor prevented the TNF-alpha-induced apoptosis and toxicity produced by catalase overexpression. |
3(0,0,0,3) | Details |
| 18782624 | Otsu K, Sato K, Sato M, Ono H, Ohba Y, Katagata Y: Impaired activation of caspase cascade during cell death induced by newly synthesized singlet generator, 1-buthylnaphthalene-4- endoperoxide. Cell Biol Int. 2008 Nov;32(11):1380-7. Epub 2008 Aug 20. The cytotoxic effect of BNPE was attenuated by but not by sodium azide. Caspase activity in a soluble protein fraction were inhibited similarly by the above three endoperoxides. |
2(0,0,0,2) | Details |
| 11195789 | Kositprapa C, Zhang B, Berger S, Canty JM Jr, Lee TC: Calpain-mediated proteolytic cleavage of troponin I induced by hypoxia or metabolic inhibition in cultured neonatal cardiomyocytes. Mol Cell Biochem. 2000 Nov;214(1-2):47-55. Inhibitors of caspases, on the other hand, suppressed cell injury caused by p53 overexpression. |
2(0,0,0,2) | Details |
| 10797567 | Chan WH, Yu JS: Inhibition of UV irradiation-induced oxidative stress and apoptotic biochemical changes in human epidermal carcinoma A431 cells by J Cell Biochem. 2000 Apr;78(1):73-84. Ultraviolet (UV) light is a strong apoptotic trigger that can induce a caspase-dependent biochemical change in cells. |
2(0,0,0,2) | Details |
| 19919184 | Veerman EC, Valentijn-Benz M, van't Hof W, Nazmi K, van Marle J, Amerongen AV: kills Candida albicans by disrupting its cell membrane. . Biol Chem. 2010 Jan;391(1):65-71. Previously, it has been reported that the fungicidal activity of PHS is based on the induction of caspase-independent apoptosis. |
1(0,0,0,1) | Details |
| 10879632 | Kumi-Diaka J, Butler A: Caspase-3 protease activation during the process of -induced apoptosis in TM4 testicular cells. Biol Cell. 2000 Apr;92(2):115-24. Caspase-3 enzymatic activity was determined using CasPASE Apoptosis Assay Kit. The overall results from all the data demonstrated that: i) exerts dose- and time-dependent effects on TM4 testis cells; ii) apoptosis is induced by lower concentrations of and necrosis induced by higher concentrations of iii) induced activation caspase-3 enzymatic activity; iv) -induction of apoptosis and necrosis was significantly inhibited by the caspase-3 inhibitor, z-DEV-FMK; v) sodium azide induced necrosis without activation of CPP32 enzymatic activity, and induction of apoptosis; and vi) -induced apoptosis was associated with activation of CPP32 enzymatic activity in the cells. |
1(0,0,0,1) | Details |
| 10707086 | Goldstein JC, Waterhouse NJ, Juin P, Evan GI, Green DR: The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol. 2000 Mar;2(3):156-62. Release of cytochrome c from mitochondria triggers activation of caspase proteases and death of a cell by apoptosis. |
1(0,0,0,1) | Details |
| 10693948 | Kaal EC, Vlug AS, Versleijen MW, Kuilman M, Joosten EA, Bar PR: Chronic mitochondrial inhibition induces selective motoneuron death in vitro: a new model for amyotrophic lateral sclerosis. J Neurochem. 2000 Mar;74(3):1158-65. We could reproduce this dose-dependent phenomenon with the complex IV inhibitor sodium azide. Furthermore, the caspase inhibitors N-benzyloxycarbonyl-Val--Asp-fluoromethyl ketone and z-Asp--Val-Asp-fluoromethyl ketone were both protective against toxicity. |
1(0,0,0,1) | Details |
| 15082229 | Cho S, Liu D, Fairman D, Li P, Jenkins L, McGonigle P, Wood A: Spatiotemporal evidence of apoptosis-mediated ischemic injury in organotypic hippocampal slice cultures. Neurochem Int. 2004 Jul;45(1):117-27. In order to ascertain the existence of the synaptic pool of sister cultures were treated with sodium azide. |
0(0,0,0,0) | Details |