Name | SUR1 |
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Synonyms | ABC36; PHHI; MRP8; HI; ABCC 8; ABCC8; ATP binding cassette transporter sub family C member 8; HHF 1… |
Name | sodium azide |
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CAS | sodium azide |
PubMed | Abstract | RScore(About this table) | |
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10864893 | McKay NG, Kinsella JM, Campbell CM, Ashford ML: Sensitivity of Kir6.2-SUR1 currents, in the absence and presence of sodium azide, to the K (ATP) channel inhibitors, ciclazindol and englitazone. Br J Pharmacol. 2000 Jun;130(4):857-66. |
41(0,1,2,6) | Details |
11082117 | Trapp S, Ashcroft FM: Direct interaction of Na-azide with the KATP channel. Br J Pharmacol. 2000 Nov;131(6):1105-12. The effects of the metabolic inhibitor sodium azide were tested on excised macropatches from XENOPUS: oocytes expressing cloned ATP-sensitive (KATP) channels of the Kir6.2/SUR1 type. 2. |
33(0,1,1,3) | Details |
14872319 | Dufer M, Haspel D, Krippeit-Drews P, Aguilar-Bryan L, Bryan J, Drews G: Oscillations of membrane potential and cytosolic Ca (2+) concentration in SUR1 (-/-) beta cells. Diabetologia. 2004 Mar;47(3):488-98. Epub 2004 Feb 11. The depolarization of DeltaPsi evoked by sodium azide was significantly lower in SUR1 (-/-) than SUR1 (+/+) cells. |
12(0,0,1,7) | Details |
13679426 | Chen M, Dong Y, Simard JM: Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain. J Neurosci. 2003 Sep 17;23(24):8568-77. |
4(0,0,0,4) | Details |
9135131 | Gribble FM, Tucker SJ, Ashcroft FM: The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide. EMBO J. 1997 Mar 17;16(6):1145-52. |
3(0,0,0,3) | Details |
10050011 | Lee K, Dixon AK, Richardson PJ, Pinnock RD: hypothalamus express KATP channels composed of Kir6.1 and SUR1 subunits. J Physiol. 1999 Mar 1;515 ( Pt 2):439-52. In cell-attached recordings, removal of extracellular or metabolic inhibition with sodium azide reduced the firing rate of a subpopulation of cells through the activation of a 65 pS channel that was blocked by the sulphonylureas and glibenclamide. 2. |
-receptive neurones in the rat ventromedial 1(0,0,0,1) | Details |
9705995 | Lee K, Dixon AK, Freeman TC, Richardson PJ: Identification of an ATP-sensitive potassium channel current in rat striatal cholinergic interneurones. J Physiol. 1998 Jul 15;510 ( Pt 2):441-53. It is concluded that cholinergic interneurones within the rat striatum exhibit a KATP channel current and that this channel is formed from Kir6.1 and SUR1 subunits. Using permeabilized patch recordings, neurones were shown to hyperpolarize in response to deprivation or metabolic poisoning with sodium azide (NaN3). |
1(0,0,0,1) | Details |
10516647 | Surah-Narwal S, Xu SZ, McHugh D, McDonald RL, Hough E, Cheong A, Partridge C, Sivaprasadarao A, Beech DJ: Block of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A. Br J Pharmacol. 1999 Oct;128(3):667-72. Metabolic poisoning of Xenopus laevis oocytes with sodium azide and application of the K+ channel opener drug diazoxide induced K+ channel currents in oocytes co-injected with cRNA for hKir6.1 and hamster sulphonylurea receptor (SUR1), but not in oocytes injected with water or cRNA for hKir6.1 or SUR1 alone. 3. |
0(0,0,0,0) | Details |