Name | OCTN2 |
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Synonyms | CDSP; SCD; High affinity sodium dependent carnitine cotransporter; OCTN 2; OCTN2; Organic cation/carnitine transporter 2; SLC22A5; Solute carrier family 22 member 5… |
Name | sodium azide |
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CAS | sodium azide |
PubMed | Abstract | RScore(About this table) | |
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10504033 | Yokogawa K, Miya K, Tamai I, Higashi Y, Nomura M, Miyamoto K, Tsuji A: Characteristics of transport in cultured human hepatoma HLF cells. J Pharm Pharmacol. 1999 Aug;51(8):935-40. The recently cloned organic cation transporter, OCTN2, isolated as a homologue of OCTN1, has been shown to be of physiological importance in the renal tubular reabsorption of filtered as a high-affinity Na+ transporter in man. The high affinity transporter was significantly inhibited by metabolic inhibitors (sodium azide, dinitrophenol, iodoacetic acid) and at low temperature (4 degrees C). |
4(0,0,0,4) | Details |
18606742 | Okura T, Hattori A, Takano Y, Sato T, Hammarlund-Udenaes M, Terasaki T, Deguchi Y: Involvement of the pyrilamine transporter, a putative organic cation transporter, in blood-brain barrier transport of Drug Metab Dispos. 2008 Oct;36(10):2005-13. Epub 2008 Jul 7. The transport was inhibited by metabolic inhibitors (rotenone and sodium azide) but was insensitive to extracellular and membrane potential for both substrates. |
0(0,0,0,0) | Details |