Protein Information

Name glutathione reductase
Synonyms GLUR; GR; GRD 1; GRD1; GRase; GSR; Glutathione reductase; GRases…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
9304813 Biagini GA, Suller MT, Finlay BJ, Lloyd D: Oxygen uptake and antioxidant responses of the free-living diplomonad Hexamita sp. J Eukaryot Microbiol. 1997 Sep-Oct;44(5):447-53.


The observed NADPH-driven glutathione reductase activity is believed to recycle oxidized thiols in order to re-establish reduced thiol levels in the cell.
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18722362 Prigol M, Wilhelm EA, Schneider CC, Nogueira CW: Protective effect of unsymmetrical dichalcogenide, a novel antioxidant agent, in vitro and an in vivo model of brain oxidative damage. Chem Biol Interact. 2008 Nov 25;176(2-3):129-36. Epub 2008 Aug 5.

The levels of lipid peroxidation and the activity of catalase, glutathione peroxidase (GPx), glutathione S-transferase (GST) and glutathione reductase (GR) were carried out in brain homogenates of SNP-injected mice.
Unsymmetrical dichalcogenides (1-3) were tested against lipid peroxidation induced by sodium nitroprusside (SNP) or malonate, and reactive species (RS) production induced by sodium azide in rat brain homogenates.
1(0,0,0,1) Details
9029274 Leeder RG, Rafeiro E, Brien JF, Mandin CC, Massey TE: Evaluation of reactive oxygen species involvement in amiodarone pulmonary toxicity in vivo and in vitro. J Biochem Toxicol. 1996;11(3):147-60.

Incubation of macrophages with AM (73 or 146 microM) for 1 hour, with or without the catalase inhibitor sodium azide (1 mM), did not result in DCF formation.
Lung glutathione reductase activity was inhibited by 66%, 6 hours following administration of 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) (20 mg/kg i.p.).
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