Protein Information

Name gp91 phox
Synonyms CGD; CGD91 PHOX; CYBB; Cytochrome B 245 heavy chain; Cytochrome B(558) beta chain; Cytochrome b(558) subunit beta; Cytochrome b 245 beta polypeptide; Cytochrome b558 subunit beta…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
20036216 Hur J, Lee P, Kim MJ, Kim Y, Cho YW: Ischemia-activated microglia induces neuronal injury via activation of gp91phox NADPH oxidase. Biochem Biophys Res Commun. 2010 Jan 15;391(3):1526-30. Epub 2009 Dec 28.

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16115042 Muranaka S, Fujita H, Fujiwara T, Ogino T, Sato EF, Akiyama J, Imada I, Inoue M, Utsumi K: Mechanism and characteristics of stimuli-dependent ROS generation in undifferentiated HL-60 cells. Antioxid Redox Signal. 2005 Sep-Oct;7(9-10):1367-76.

Five subunits of NADPH oxidase, namely, gp91 (phox), p22 (phox), p67 (phox), p47 (phox), and Rac 2, were detected in undifferentiated HL-60 cells by immunoblotting analysis.
Genistein, staurosporine, uric acid, and sodium azide inhibited the ROS generation in undifferentiated HL-60 cells in a similar way to that in undifferentiated neutrophils.
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