Protein Information

Name casein
Synonyms Alpha; Alpha s1 casein; Alpha s1 casein precursor; CASA; CSN 1; CSN1; CSN1S1; Casein…

Compound Information

Name sodium azide
CAS sodium azide

Reference List

PubMed Abstract RScore(About this table)
8225131 van Boekel MA, Weerens CN, Holstra A, Scheidtweiler CE, Alink GM: Antimutagenic effects of casein and its digestion products. . Food Chem Toxicol. 1993 Oct;31(10):731-7.

Casein was very effective against benzo [a] pyrene, N-methylnitrosourea and nitrosated 4-chloroindole, and was less effective towards sodium azide and N-nitroquinoline-1-oxide (NQO).
23(0,0,3,8) Details
16045896 Haddadi K, Moussaoui F, Hebia I, Laurent F, Le Roux Y: E. coli proteolytic activity in milk and casein breakdown. . Reprod Nutr Dev. 2005 Jul-Aug;45(4):485-96.

The first part consisted in the incubation of 104 cfu.mL (-1) of the E. coli strain in raw milk at 37 degrees C for 24 h; the same milk was also incubated with 0.04% sodium azide.
2(0,0,0,2) Details
8751977 Herrmann G, Wlaschek M, Bolsen K, Prenzel K, Goerz G, Scharffetter-Kochanek K: Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts. J Invest Dermatol. 1996 Sep;107(3):398-403.

Gelatin and casein zymography revealed increased proteolytic activity of MMP-2 and MMP-3 in blister fluids of patients with porphyria cutanea tarda, indicating that similar events may occur in vivo.
Using deuterium oxide as enhancer and sodium azide as quencher of singlet oxygen, we could increase or reduce MMP synthesis, suggesting that singlet oxygen is the major intermediate in the upregulation of MMPs after irradiation of uroporphyrin-pretreated fibroblasts.
1(0,0,0,1) Details
18093810 Shchipunov Y, Shipunova N: Regulation of silica morphology by proteins serving as a template for mineralization. Colloids Surf B Biointerfaces. 2008 May 1;63(1):7-11. Epub 2007 Nov 9.


Here it is demonstrated by using a novel biocompatible precursor that common proteins - albumin, caseins and gelatin - can mediate formation of hybrid nanocomposite materials through catalyzing the sol-gel processes and templating silica generated in situ.
1(0,0,0,1) Details
9334451 Pantigoso C, Escobar E, Malaga O, Yarleque A: [Isolation and some properties of the proteinase atroxin from the venom of the snake Bothrops atrox]. Acta Cient Venez. 1996;47(1):67-73.

It had a high activity on casein being 7.4 optimus pH.
On the other hand, 0.133 mumoles of Ca2+ and Mg2+, and Zn2+ ions (0.266 mumoles) were activators, while EDTA (0.20 mumoles) and sodium azide (0.053 mumoles) were inhibitors.
1(0,0,0,1) Details