| Name | TH1 |
|---|---|
| Synonyms | HSPC130; NELF C/D; NELF C; NELF D; NELFC; NELFD; Negative elongation factor C/D; Negative elongation factor proteins C and D… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7905205 | Castedo M, Pelletier L, Pasquier R, Druet P: Improvement of TH1 functions during the regulation phase of mercury disease in brown Norway rats. Scand J Immunol. 1994 Feb;39(2):144-50. The TH2-mediated immune abnormalities observed in BN rats injected with mercuric chloride (HgCl2) are self-limited and it is probable that this regulation phase involves TH1-like cells. |
33(0,1,1,3) | Details |
| 8258322 | Saoudi A, Kuhn J, Huygen K, de Kozak Y, Velu T, Goldman M, Druet P, Bellon B: TH2 activated cells prevent experimental autoimmune uveoretinitis, a TH1-dependent autoimmune disease. Eur J Immunol. 1993 Dec;23(12):3096-103. Mercuric chloride (HgCl2) injections protect Brown-Norway) F1 (F1) rats against experimental autoimmune uveoretinitis (EAU) induced by immunization with the retinal S antigen (S-Ag); in contrast HgCl2-injected F1 rats develop EAU following transfer of lymph node (LN) cells from rats immunized with S-Ag alone. |
3(0,0,0,3) | Details |
| 8105582 | Saoudi A, Kuhn J, Huygen K, de Kozak Y, Velu T, Goldman M, Druet P, Bellon B: Role of the TH1-TH2 balance in the development of autoimmunity in rats. Transplant Proc. 1993 Oct;25(5):2824-5. |
1(0,0,0,1) | Details |
| 7697730 | van der Meide PH, de Labie MC, Botman CA, Aten J, Weening JJ: suppresses IFN-gamma production in the spleen of mercuric chloride-exposed brown Norway rats. Cell Immunol. 1995 Apr 1;161(2):195-206. Since BN rats develop a TH2-biased polyclonal autoimmune syndrome upon exposure to HgCl2, whereas Lewis rats exhibit a resistant phenotype, possibly by generating a protective TH1 response, downregulation of IFN-gamma production may be a critical denominator in the disease process. |
1(0,0,0,1) | Details |
| 7704901 | van der Meide PH, Groenestein RJ, de Labie MC, Aten J, Weening JJ: Susceptibility to mercuric chloride-induced glomerulonephritis is age-dependent: study of the role of IFN-gamma. Cell Immunol. 1995 Apr 15;162(1):131-7. FACScan analysis of splenocytes from old and young rats revealed a defined increase in the frequency of CD45RB (RC)+/CD4+ T cells in the splenocyte population of older rats, suggesting an age-related shift to a more TH1-like phenotype. |
1(0,0,0,1) | Details |