| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8535296 | Aijafari AA: Mercuric chloride effects on the kinetic parameters of human erythrocyte membrane bound acetylcholinesterase. Biochem Mol Biol Int. 1995 Aug;36(6):1243-53. |
249(3,3,4,4) | Details |
| 9096309 | Shin I, Kreimer D, Silman I, Weiner L: Membrane-promoted unfolding of acetylcholinesterase: a possible mechanism for insertion into the lipid bilayer. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):2848-52. Chemical modification of Cys231 by mercuric chloride produces initially a quasinative state of Torpedo acetylcholinesterase which, at room temperature, undergoes spontaneous transition to a molten globule state with a half-life of 1-2 hr. |
33(0,1,1,3) | Details |
| 8215912 | Lakshmana MK, Desiraju T, Raju TR: Mercuric chloride-induced alterations of levels of and acetylcholine esterase activity in different regions of rat brain during postnatal development. Arch Toxicol. 1993;67(6):422-7. |
8(0,0,1,3) | Details |
| 1982872 | Gill TS, Tewari H, Pande J: Use of the fish enzyme system in monitoring water quality: effects of mercury on tissue enzymes. Comp Biochem Physiol C. 1990;97(2):287-92. Rosy barb (Puntius conchonius) were exposed to 181 micrograms/l mercuric chloride for 48 h and the activity of acid and alkaline phosphatases (AcP and AIP), aspartate aminotransferase (AAT), alanine aminotransferase (AIAT), lactic dehydrogenase (LDH), and acetylcholinesterase (AchE) were measured in vivo in several organs. 2. |
6(0,0,1,1) | Details |
| 15139388 | Moretto MB, Lermen CL, Morsch VM, Bohrer D, Ineu RP, da Silva AC, Balz D, Schetinger MR: Effect of subchronic treatment with mercury on NTPDase, 5'-nucleotidase and acetylcholinesterase from cerebral cortex of rats. J Trace Elem Med Biol. 2004;17(4):255-60. |
5(0,0,0,5) | Details |
| 19446626 | Franciscato C, Goulart FR, Lovatto NM, Duarte FA, Flores EM, Dressler VL, Peixoto NC, Pereira ME: ZnCl2 exposure protects against behavioral and acetylcholinesterase changes induced by HgCl2. Int J Dev Neurosci. 2009 Aug;27(5):459-68. Epub 2009 May 14. |
3(0,0,0,3) | Details |
| 17355286 | Frasco MF, Colletier JP, Weik M, Carvalho F, Guilhermino L, Stojan J, Fournier D: Mechanisms of cholinesterase inhibition by inorganic mercury. FEBS J. 2007 Apr;274(7):1849-61. Epub 2007 Mar 12. Our results show that when a free sensitive sulfhydryl group is present in the enzyme, as in Torpedo californica acetylcholinesterase, inhibition is irreversible and follows pseudo-first-order kinetics that are completed within 1 h in the micromolar range. |
2(0,0,0,2) | Details |
| 11495025 | El-Demerdash FM: Effects of and mercury on the enzymatic activities and lipid peroxidation in brain, liver, and blood of rats. J Environ Sci Health B. 2001 Jul;36(4):489-99. The present study compares the effects of Se as selenite (Na2SeO3) and Hg as mercuric chloride (HgCl2) separately and in combination. The following biochemical alterations occurred in response to Hg treatment: protein content (brain and liver), acetylcholinesterase (AChE) (brain and serum), acid and alkaline (AcP and AlP) phosphatases (plasma and liver) and glutathione S-transferase (GST) (plasma and liver) activities were significantly (P <0.05) decreased, while lactate dehydrogenase (LDH) (plasma, brain and liver), and alanine aminotransferase (AST, ALT) (serum and liver) activities were significantly increased. |
1(0,0,0,1) | Details |
| 8476528 | Ghosh N, Bhattacharya S: Acute phase response of rabbit to HgCl2 and CdCl2. Biomed Environ Sci. 1993 Mar;6(1):1-7. A variety of changes occur in the rabbit under metal stress which include the appearance of the acute phase protein, C-reactive protein in the serum and significant reduction in the serum titres of albumin and acetylcholinesterase. |
1(0,0,0,1) | Details |
| 17582519 | Trielli F, Amaroli A, Sifredi F, Marchi B, Falugi C, Corrado MU: Effects of xenobiotic compounds on the cell activities of Euplotes crassus, a single-cell eukaryotic test organism for the study of the pollution of marine sediments. Aquat Toxicol. 2007 Aug 1;83(4):272-83. Epub 2007 May 13. In addition, as it is well-known that the inhibition of acetylcholinesterase activity represents a specific biomarker of exposure to OP and pesticides in higher organisms, initially the presence of cholinesterase (ChE) activity was detected in E. crassus, using cytochemical, spectrophotometric and electrophoretic methods. |
1(0,0,0,1) | Details |