| Name | CTLA 4 |
|---|---|
| Synonyms | CD152; GSE; CELIAC 3; CELIAC3; CTLA4; CD152 antigen; CTLA 4; Cytotoxic T lymphocyte antigen 4… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12874254 | Zheng Y, Monestier M: Inhibitory signal override increases susceptibility to mercury-induced autoimmunity. J Immunol. 2003 Aug 1;171(3):1596-601. In susceptible mice treated with mercuric chloride (HgCl (2)), administration of a blocking anti-CTLA-4 Ab resulted in a further increase in anti-nucleolar autoantibodies and in total serum IgG1 levels. |
83(1,1,1,3) | Details |
| 15494542 | Pollard KM, Arnush M, Hultman P, Kono DH: Costimulation requirements of induced murine systemic autoimmune disease. . J Immunol. 2004 Nov 1;173(9):5880-7. Absence of CTLA-4 expression in CD40L-/- mice suggests that signaling via both CD28 and CD40L is important for T cell activation and subsequent autoimmunity in mHgIA. |
1(0,0,0,1) | Details |
| 8666905 | Biancone L, Andres G, Ahn H, Lim A, Dai C, Noelle R, Yagita H, De Martino C, Stamenkovic I: Distinct regulatory roles of lymphocyte costimulatory pathways on T helper type-2 mediated autoimmune disease. J Exp Med. 1996 Apr 1;183(4):1473-81. Inhibition of CD40-CD40-L and CTLA4/CD28-B7s interactions by anti-CD40-L antibody and soluble CTLA4-immunoglobulin (Ig) fusion protein, respectively, abrogated the autoimmune disease without affecting interleukin 4 (IL-4) production, showing the importance of physical contact between T and B lymphocytes in the Th2-mediated process. |
1(0,0,0,1) | Details |