| Name | cytochrome c |
|---|---|
| Synonyms | CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16764493 | Lee JH, Youm JH, Kwon KS: [Mercuric chloride induces apoptosis in MDCK cells] . J Prev Med Public Health. 2006 May;39(3):199-204. MDCK cells were cultured for 6-24 hr in vitro in various concentrations (0.1-100 M) of HgCl2, and the markers of apoptosis or cell death were assayed, including DNA fragmentation, caspase-3 activity andwestern blotting of cytochrome c. |
4(0,0,0,4) | Details |
| 18603796 | Sugio T, Fujii M, Ninomiya Y, Kanao T, Negishi A, Takeuchi F: Reduction of Hg2+ with reduced mammalian cytochrome c by cytochrome c oxidase purified from a mercury-resistant acidithiobacillus ferrooxidans strain, MON-1. Biosci Biotechnol Biochem. 2008 Jul;72(7):1756-63. Epub 2008 Jul 7. The cytochrome c oxidase activities of strains AP19-3 and ATCC 23270 were completely inhibited by 1 muM and 5 muM of mercuric chloride respectively. |
4(0,0,0,4) | Details |
| 11068922 | Shenker BJ, Guo TL, Shapiro IM: Mercury-induced apoptosis in human lymphoid cells: evidence that the apoptotic pathway is mercurial species dependent. Environ Res. 2000 Oct;84(2):89-99. Since mitochondrial dysfunction and the development of a permeability transition may result in the release of cytochrome c, a factor that promotes apoptosis, we assessed the abilities of both species of mercury to induce the translocation of cytochrome c from mitochondria to the cytosol. |
3(0,0,0,3) | Details |
| 12505371 | Araragi S, Kondoh M, Kawase M, Saito S, Higashimoto M, Sato M: Mercuric chloride induces apoptosis via a mitochondrial-dependent pathway in human leukemia cells. Toxicology. 2003 Feb 14;184(1):1-9. The release of cytochrome c (Cyt c) from mitochondria into the cytosol, which is an initiator of the activation of caspase cascades, was also observed in HgCl (2)-treated HL-60 cells. |
1(0,0,0,1) | Details |
| 12215206 | Shenker BJ, Pankoski L, Zekavat A, Shapiro IM: Mercury-induced apoptosis in human lymphocytes: caspase activation is linked to redox status. Antioxid Redox Signal. 2002 Jun;4(3):379-89. We have previously shown that methyl mercuric chloride (MeHgCl) is a potent human T-cell apoptogen; moreover, mitochondria appear to be a target organelle for the induction of cell death. We next observed the release of cytochrome c from mitochondria into the cytosol; significant translocation was noted between 4 and 8 h following treatment with mercury. |
1(0,0,0,1) | Details |
| 9878595 | Guo TL, Miller MA, Shapiro IM, Shenker BJ: Mercuric chloride induces apoptosis in human T lymphocytes: evidence of mitochondrial dysfunction. Toxicol Appl Pharmacol. 1998 Dec;153(2):250-7. |
0(0,0,0,0) | Details |