| Name | costimulatory molecules |
|---|---|
| Synonyms | 4Ig B7 H3; B7 homolog 3; B7 H3; B7H3; CD276; CD276 antigen; CD276 antigen precursor; CD276 molecule… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17015760 | Vinay DS, Kim JD, Kwon BS: Amelioration of mercury-induced autoimmunity by 4-1BB. . J Immunol. 2006 Oct 15;177(8):5708-17. In certain strains of mice, subtoxic doses of HgCl2 (mercuric chloride; mercury) induce a complex autoimmune condition characterized by the production of antinucleolar IgG Abs, lymphoproliferation, increased serum levels of IgG1/IgE Abs, and deposition of renal immune complexes. 4-1BB is an important T cell costimulatory molecule that has been implicated in T cell proliferation and cytokine production, especially production of IFN-gamma. |
31(0,1,1,1) | Details |
| 8633208 | Roos A, Claessen N, Weening JJ, Aten J: Enhanced T lymphocyte expression of LFA-1, ICAM-1, and the TNF receptor family member OX40 in HgCl2-induced systemic autoimmunity. Scand J Immunol. 1996 May;43(5):507-18. Injection of mercuric chloride into Brown Norway (BN) rats induces a T lymphocyte-dependent autoimmune syndrome. In order to investigate whether modification of adhesion and costimulatory molecules on T lymphocytes may be involved in early T lymphocyte activation by HgCl2, the authors analysed expression of these molecules in peripheral lymph node cells from BN rats at day 4 after injection of HgCl2. |
2(0,0,0,2) | Details |