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Pu MY, Akhand AA, Kato M, Koike T, Hamaguchi M, Suzuki H, Nakashima I: Mercuric chloride mediates a protein sulfhydryl modification-based pathway of signal transduction for activating Src kinase which is independent of the phosphorylation/dephosphorylation of a carboxyl terminal tyrosine. J Cell Biochem. 1996 Oct;63(1):104-14.
Correspondingly, CNBr cleavage mapping of phosphopeptides for autophosphorylated c-Src protein demonstrated selective promotion of phosphorylation at Y416 in HgCl2-treated cells without obvious change in the phosphorylation level at Y527. |
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