| Name | alanine aminotransferase |
|---|---|
| Synonyms | AAT1; AAT1; GPT; ALT 1; ALT1; Alanine aminotransferase; Alanine aminotransferase 1; GPT 1… |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16964587 | Brandao R, Santos FW, Farina M, Zeni G, Bohrer D, Rocha JB, Nogueira CW: Antioxidants and metallothionein levels in mercury-treated mice. Cell Biol Toxicol. 2006 Nov;22(6):429-38. Epub 2006 Sep 11. Mice received a single dose of mercuric chloride (HgCl2, 4.6 mg/kg, subcutaneously) for three consecutive days. |
0(0,0,0,0) | Details |
| 8580532 | Shakoori AR, Kokab R, Mahjabeen G, Anjum F, Ali SS: Effect of mercuric chloride on the activities of some hepatic enzymes of regenerating rabbit liver following partial hepatectomy. Acta Physiol Pharmacol Ther Latinoam. 1995;45(3):177-84. After withdrawal of HgCl2 treatment for 10 days, the LDH and glutamate pyruvate transaminase (GPT) activities showed 56% and 40% decrease, respectively, while alkaline phosphatase (AkP) activity increased 4.12 fold. |
1(0,0,0,1) | Details |
| 11495025 | El-Demerdash FM: Effects of and mercury on the enzymatic activities and lipid peroxidation in brain, liver, and blood of rats. J Environ Sci Health B. 2001 Jul;36(4):489-99. The present study compares the effects of Se as selenite (Na2SeO3) and Hg as mercuric chloride (HgCl2) separately and in combination. The following biochemical alterations occurred in response to Hg treatment: protein content (brain and liver), acetylcholinesterase (AChE) (brain and serum), acid and alkaline (AcP and AlP) phosphatases (plasma and liver) and glutathione S-transferase (GST) (plasma and liver) activities were significantly (P <0.05) decreased, while lactate dehydrogenase (LDH) (plasma, brain and liver), and alanine aminotransferase (AST, ALT) (serum and liver) activities were significantly increased. |
1(0,0,0,1) | Details |
| 1982872 | Gill TS, Tewari H, Pande J: Use of the fish enzyme system in monitoring water quality: effects of mercury on tissue enzymes. Comp Biochem Physiol C. 1990;97(2):287-92. Rosy barb (Puntius conchonius) were exposed to 181 micrograms/l mercuric chloride for 48 h and the activity of acid and alkaline phosphatases (AcP and AIP), aspartate aminotransferase (AAT), alanine aminotransferase (AIAT), lactic dehydrogenase (LDH), and acetylcholinesterase (AchE) were measured in vivo in several organs. 2. |
6(0,0,1,1) | Details |
| 7884643 | Anjum F, Shakoori AR: Sublethal effects of inorganic mercury on the body growth rate and liver function enzymes of phenobarbitone-pretreated and promethazine-pretreated rabbits. J Environ Pathol Toxicol Oncol. 1994;13(2):125-32. After phenobarbitone (PB) treatment, the serum transaminase (GOT), glutamate pyruvate transaminase (GPT), isocitrate dehydrogenase (ICDH), and lactate dehydrogenase (LDH) activities decreased to 31%, 77%, 20%, and 27%, respectively, whereas the serum alkaline phosphatase (AP) activity increased 54%. After mercuric chloride (HgCl2) treatment, the serum GOT, GPT, LDH, and ICDH activities decreased 69%, 83%, 11%, and 48%, respectively. |
1(0,0,0,1) | Details |
| 17706852 | Sharma MK, Sharma A, Kumar A, Kumar M: Spirulina fusiformis provides protection against mercuric chloride induced oxidative stress in Swiss albino mice. Food Chem Toxicol. 2007 Dec;45(12):2412-9. Epub 2007 Jun 28. Supplementation of Spirulina (800 mg/kg body weight orally, in olive oil, along with mercuric chloride) for 40 days resulted in decreased LPO level, serum and serum glutamate pyruvate transaminase activity along with increase in liver level. |
6(0,0,1,1) | Details |
| 18443381 | El-Shenawy SM, Hassan NS: Comparative evaluation of the protective effect of and garlic against liver and kidney damage induced by mercury in the rats. Pharmacol Rep. 2008 Mar-Apr;60(2):199-208. The results revealed that the rats injected with HgCl (2) showed a significant increase in levels of blood urea (BUN), serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) by 29.3%, 62.5%, 29.46% and 30.61%, respectively, while alkaline phosphatase (ALP) showed a significant decrease by 22.6% as compared with saline control group. |
1(0,0,0,1) | Details |
| 7482568 | Bucio L, Souza V, Albores A, Sierra A, Chavez E, Carabez A, Gutierrez-Ruiz MC: Cadmium and mercury toxicity in a human fetal hepatic cell line (WRL-68 cells). Toxicology. 1995 Sep 18;102(3):285-99. Cell damage was also measured by alanine aminotransferase (ALAT) and aspartate aminotransferase (ASAT) activities. |
1(0,0,0,1) | Details |
| 15977196 | Bando I, Reus MI, Andres D, Cascales M: Endogenous antioxidant defence system in rat liver following mercury oral intoxication. J Biochem Mol Toxicol. 2005;19(3):154-61. HgCl2 at the doses of 0.1 mg/kg produced liver damage which that was detected by a slight increase in serum alanine aminotransferase and gamma glutamyl transferase. |
1(0,0,0,1) | Details |
| 16841248 | Brandao R, Santos FW, Zeni G, Rocha JB, Nogueira CW: DMPS and induced renal toxicity in mice exposed to mercury. Biometals. 2006 Aug;19(4):389-98. Acute effects of mercuric chloride (HgCl2) were evaluated on mice. Plasma (AST) and alanine (ALT) aminotransferase activities, as well as urea and levels were determined. |
1(0,0,0,1) | Details |
| 18758054 | Ghosh A, Sil PC: A protein from Cajanus indicus Spreng protects liver and kidney against mercuric chloride-induced oxidative stress. Biol Pharm Bull. 2008 Sep;31(9):1651-8. In addition, HgCl (2) increased the activities of serum marker enzymes (namely, glutamate pyruvate transaminase, GPT and alkaline phosphatase, ALP), blood urea and serum tumor necrosis factor alpha (TNF-alpha) level along with hepatic and renal lipid peroxidation. |
1(0,0,0,1) | Details |
| 12587743 | Sharma MK, Kumar M, Kumar A: Ocimum sanctum aqueous leaf extract provides protection against mercury induced toxicity in Swiss albino mice. Indian J Exp Biol. 2002 Sep;40(9):1079-82. In serum of HgCl2 treated mice there was significant elevation in serum transaminase (SGOT) and serum glutamate pyruvate transaminase (SGPT) activities but significant decline in the alkaline phosphatase activity. |
1(0,0,0,1) | Details |