Protein Information

Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name mercuric chloride
CAS

Reference List

PubMed Abstract RScore(About this table)
8216361 McCracken NW, Blain PG, Williams FM: Human xenobiotic metabolizing esterases in liver and blood. Biochem Pharmacol. 1993 Oct 5;46(7):1125-9.

Inhibitory studies using paraoxon, bis-nitrophenol phosphate and mercuric chloride indicated fluazifop-butyl hydrolysis involved carboxylesterase in liver microsomes and cytosol, and cholinesterase and carboxylesterase in plasma.
31(0,1,1,1) Details
17355286 Frasco MF, Colletier JP, Weik M, Carvalho F, Guilhermino L, Stojan J, Fournier D: Mechanisms of cholinesterase inhibition by inorganic mercury. FEBS J. 2007 Apr;274(7):1849-61. Epub 2007 Mar 12.

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18639316 Frasco MF, Fournier D, Carvalho F, Guilhermino L: Does mercury interact with the inhibitory effect of dichlorvos on Palaemon serratus (Crustacea: Decapoda) cholinesterase?. Sci Total Environ. 2008 Oct 1;404(1):88-93. Epub 2008 Jul 17.

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17582519 Trielli F, Amaroli A, Sifredi F, Marchi B, Falugi C, Corrado MU: Effects of xenobiotic compounds on the cell activities of Euplotes crassus, a single-cell eukaryotic test organism for the study of the pollution of marine sediments. Aquat Toxicol. 2007 Aug 1;83(4):272-83. Epub 2007 May 13.


In addition, as it is well-known that the inhibition of acetylcholinesterase activity represents a specific biomarker of exposure to OP and carbamate pesticides in higher organisms, initially the presence of cholinesterase (ChE) activity was detected in E. crassus, using cytochemical, spectrophotometric and electrophoretic methods.
1(0,0,0,1) Details
1459653 Ghosh S, Bhattacharya S: Elevation of C-reactive protein in serum of Channa punctatus as an indicator of water pollution. Indian J Exp Biol. 1992 Aug;30(8):736-7.


The carbamate compound, carbaryl demonstrated a biphasic response to CRP level which may be correlated with the reversible type of anticholinesterase property of this compound while Metacid-50 is an irreversible type of anticholinesterase agent.
1(0,0,0,1) Details
10859148 Hewitt PG, Perkins J, Hotchkiss SA: Metabolism of fluroxypyr, fluroxypyr methyl ester, and the herbicide fluroxypyr methylheptyl ester. Drug Metab Dispos. 2000 Jul;28(7):755-9.


Mercuric chloride (an inhibitor of A-esterase and arylesterase) and eserine (a cholinesterase inhibitor) had no inhibitory effect on the hydrolysis of FPM or FPMH.
0(0,0,0,0) Details