Protein Information

Name K12
Synonyms K12; Protein K12; SECTM 1; SECTM1; Secreted and transmembrane 1; Secreted and transmembrane protein 1; Secreted and transmembrane protein 1 precursor; Protein K12s…

Compound Information

Name mercuric chloride
CAS

Reference List

PubMed Abstract RScore(About this table)
12403178 Kholodii G, Bogdanova E: Tn5044-conferred mercury resistance depends on temperature: the complexity of the character of thermosensitivity. Genetica. 2002 Jun;115(2):233-41.

Escherichia coli K12 containing the transposon Tn5044 mer operon (merR, T, P, C, and A genes) is resistant to mercuric chloride at 30 degrees C but sensitive to this compound at 37-41.5 degrees C.
6(0,0,1,1) Details
9462432 Speakman AJ, Binns SH, Osborn AM, Corkill JE, Kariuki S, Saunders JR, Dawson S, Gaskell RM, Hart CA: Characterization of antibiotic resistance plasmids from Bordetella bronchiseptica. J Antimicrob Chemother. 1997 Dec;40(6):811-6.

Only two of these plasmids, pLV1400 and pLV1401, were self-transmissible to Escherichia coli K12; both plasmids encoded resistance to ampicillin, tetracycline, sulphonamides, streptomycin and mercuric chloride, and were of incompatibility group P (IncP).
6(0,0,1,1) Details
15057474 Gupta N, Ali A: Mercury volatilization by R factor systems in Escherichia coli isolated from aquatic environments of India. Curr Microbiol. 2004 Feb;48(2):88-96.

Ten Escherichia coli strains isolated from five different aquatic environments representing three distinct geographical regions of India showed significantly high levels of tolerance to the inorganic form of mercury, i.e., mercuric chloride (HgCl (2)).
The transfer of mercury resistance from these wild-type strains to the mercury-sensitive, naladixic acid-resistant E. coli K12 (F (-) lac (+)) strain used as a recipient was observed in six of the nine strains tested.
1(0,0,0,1) Details
16110915 Franiczek R, Krzyzanowska B, Dolna I, Mokracka G, Szufnarowski K: Extended-spectrum beta-lactamase-conferring transferable resistance to different antimicrobial agents in Enterobacteriaceae isolated from bloodstream infections. Folia Microbiol. 2005;50(2):119-24.

Eleven out of the 20 ESBL-positive isolates transferred oxyimino-beta-lactam resistance to E. coli K12 C600 recipient strain with a frequency of 10 (-8) - 10 (-1) per donor cell.
Resistances to aminoglycosides, tetracycline and mercuric chloride were, in some cases, co-transferred with oxyimino-beta-lactam resistance, suggesting that various resistance determinants were carried by the same conjugative plasmids.
1(0,0,0,1) Details