| Name | acetylcholine receptor (protein family or complex) |
|---|---|
| Synonyms | Acetylcholine receptor; Acetylcholine receptors |
| Name | mercuric chloride |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12130716 | Mirzoian A, Luetje CW: Modulation of neuronal nicotinic acetylcholine receptors by mercury. J Pharmacol Exp Ther. 2002 Aug;302(2):560-7. Mercuric chloride exerted a biphasic modulatory effect on rat neuronal nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus laevis oocytes as heteromers of the alpha3 or alpha4 and beta2 or beta4 subunits. |
7(0,0,1,2) | Details |
| 18439770 | Vidal L, Duran R, Faro LR, Alfonso M: Involvement of nicotinic and muscarinic acetylcholine receptors on striatal HgCl2-induced release in freely moving rats. Toxicol Lett. 2008 May 30;178(3):181-4. Epub 2008 Mar 21. |
3(0,0,0,3) | Details |
| 15885266 | Basu N, Stamler CJ, Loua KM, Chan HM: An interspecies comparison of mercury inhibition on muscarinic acetylcholine receptor binding in the cerebral cortex and cerebellum. Toxicol Appl Pharmacol. 2005 May 15;205(1):71-6. |
1(0,0,0,1) | Details |
| 9089697 | Egorova A, Hoshi N, Knijnik R, Shahidullah M, Hashii M, Noda M, Higashida H: Sulfhydryl modification inhibits K+ (M) current with kinetics close to in rodent NG108-15 cells. Neurosci Res. 1997 Jan;27(1):35-44. The effects of sulfhydryl reagents on M-type voltage-dependent currents (IK (M)) were examined in NG108-15 cells transformed to express ml muscarinic acetylcholine receptors (mAChRs), a NGPM1-27 clone. |
1(0,0,0,1) | Details |
| 7641227 | Fejtl M, Gyori J, Carpenter DO: Mercuric (II) modulates single-channel properties of carbachol-activated Cl- channels in cultured neurons of Aplysia californica. Cell Mol Neurobiol. 1994 Dec;14(6):665-74. Inorganic Hg2+ affects the acetylcholine receptor at lower concentrations than previously reported. |
1(0,0,0,1) | Details |
| 18036150 | Lobo IA, Harris RA, Trudell JR: Cross-linking of sites involved with action between transmembrane segments 1 and 3 of the glycine receptor following activation. J Neurochem. 2008 Mar;104(6):1649-62. Epub 2007 Nov 23. Application of cross-linking (mercuric chloride) or oxidizing agents had no significant effect on the response of wild-type receptors or the single mutants. Molecular modeling was used to thread the glycine receptor sequence onto a nicotinic acetylcholine receptor template, further demonstrating that I229 and A288 are near-neighbors that can cross-link and providing evidence that these residues contribute to a single binding cavity. |
1(0,0,0,1) | Details |
| 15045580 | Miller TJ, Grow WA: Mercury decreases the frequency of induced but not spontaneous clustering of acetylcholine receptors. Cell Tissue Res. 2004 May;316(2):211-9. Epub 2004 Mar 25. Specifically, we asked whether the inorganic metal mercury interfered with the fusion of myoblasts into myotubes, acetylcholine receptor (AChR) clustering, or the agrin signaling events that precede AChR clustering. C2C12 myotubes grown in culture medium containing 10 microM mercuric chloride were morphologically indistinguishable from control myotubes at the light-microscopic level, and myoblasts fused into myotubes normally. |
1(0,0,0,1) | Details |