Protein Information

Name arylesterase
Synonyms A esterase 1; Aromatic esterase 1; Arylesterase; ESA; Esterase A; K 45; PON; PON 1…

Compound Information

Name mercuric chloride
CAS

Reference List

PubMed Abstract RScore(About this table)
17664252 Jewell C, Ackermann C, Payne NA, Fate G, Voorman R, Williams FM: Specificity of procaine and ester hydrolysis by human, minipig, and rat skin and liver. Drug Metab Dispos. 2007 Nov;35(11):2015-22. Epub 2007 Jul 30.

Rat skin and liver esterase activity was inhibited additionally by phenylmethylsulfonyl fluoride and the arylesterase inhibitor mercuric chloride, indicating a different esterase profile.
32(0,1,1,2) Details
8216361 McCracken NW, Blain PG, Williams FM: Human xenobiotic metabolizing esterases in liver and blood. Biochem Pharmacol. 1993 Oct 5;46(7):1125-9.

Inhibitory studies using paraoxon, bis-nitrophenol phosphate and mercuric chloride indicated fluazifop-butyl hydrolysis involved carboxylesterase in liver microsomes and cytosol, and cholinesterase and carboxylesterase in plasma.
Phenylacetate hydrolysis involved arylesterase in plasma, both arylesterase and carboxylesterase in liver microsomes and carboxylesterase in liver cytosol.
1(0,0,0,1) Details
10859148 Hewitt PG, Perkins J, Hotchkiss SA: Metabolism of fluroxypyr, fluroxypyr methyl ester, and the herbicide fluroxypyr methylheptyl ester. Drug Metab Dispos. 2000 Jul;28(7):755-9.


Mercuric chloride (an inhibitor of A-esterase and arylesterase) and eserine (a cholinesterase inhibitor) had no inhibitory effect on the hydrolysis of FPM or FPMH.
0(0,0,0,0) Details