Protein Information

Name beta 2 microglobulin
Synonyms B2M; Beta 2 microglobulin; Beta 2 microglobulin precursor; CDABP0092; HDCMA22P; Beta 2 microglobulins; Beta 2 microglobulin precursors

Compound Information

Name mercuric chloride
CAS

Reference List

PubMed Abstract RScore(About this table)
8015651 Thielemans N, Lauwerys R, Bernard A: Competition between albumin and low-molecular-weight proteins for renal tubular uptake in experimental nephropathies. Nephron. 1994;66(4):453-8.

We have examined the urinary excretion of albumin and of 2 low-M (r) proteins, beta 2-microglobulin and cystatin C, in rats treated with toxins affecting primarily the glomerulus (puromycin amino-nucleoside and Adriamycin) or the tubule (mercuric chloride and maleic acid).
7(0,0,1,2) Details
9644989 Rogovyi IuE: [Beta 2-microglobulin as a criterion of dysfunction in the regulation of proximal tubular activity in mercuric chloride-induced nephropathy]. Urol Nefrol. 1998 May-Jun;(3):36-8.
6(0,0,1,1) Details
9352627 Yoshida M, Satoh H, Igarashi M, Akashi K, Yamamura Y, Yoshida K: Acute mercury poisoning by intentional ingestion of mercuric chloride. . Tohoku J Exp Med. 1997 Aug;182(4):347-52.

One month after ingestion, renal function recovered to normal as judged by serum creatine and blood urea nitrogen levels, although the beta 2-microglobulin level in urine was still elevated.
1(0,0,0,1) Details
1280082 Bernard AM, Collette C, Lauwerys R: Renal effects of in utero exposure to mercuric chloride in rats. Arch Toxicol. 1992;66(7):508-13.

Both mothers and newborns developed a transient renal dysfunction resulting in an increased urinary excretion of beta 2-microglobulin and albumin.
1(0,0,0,1) Details