Name | GSTT1 |
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Synonyms | GST class theta; GST class theta 1; GSTT 1; GSTT1; GSTT1 protein; Glutathione S transferase theta 1; Glutathione transferase T1 1; glutathione S transferase T1… |
Name | methyl bromide |
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CAS | bromomethane |
PubMed | Abstract | RScore(About this table) | |
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8704864 | Garnier R, Rambourg-Schepens MO, Muller A, Hallier E: Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning. Occup Environ Med. 1996 Mar;53(3):211-15. Seven weeks after the accident, blood samples were drawn from both patients, for measurement of glutathione transferase activity in erythrocytes (conjugator status--that is, GSTT1 phenotype) and measurement of binding products of methyl bromide with blood proteins. |
87(1,1,2,2) | Details |
10650922 | Thier R, Wiebel FA, Bolt HM: Differential substrate behaviours of ethylene oxide and propylene oxide towards human glutathione transferase theta hGSTT1-1. Arch Toxicol. 1999 Nov;73(8-9):489-92. This sequence of reactivities of homologous epoxides towards GSTT1-1 contrasts to the sequence observed in homologous alkyl halides (methyl bromide, MBr; ethyl EtBr; n-propyl PrBr) where the relative sequence MeBr >> EtBr > PrBr is observed. |
9(0,0,1,4) | Details |
12872524 | Thier R, Bruning T, Roos PH, Rihs HP, Golka K, Ko Y, Bolt HM: Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. Int J Hyg Environ Health. 2003 Jun;206(3):149-71. Human phenotyping is facilitated by the GST activity towards methyl bromide or ethylene oxide in erythrocytes which is representative of the metabolic GSTT1 competence of the entire organism. |
9(0,0,1,4) | Details |
11305778 | Muller M, Voss M, Heise C, Schulz T, Bunger J, Hallier E: High-performance liquid chromatography/fluorescence detection of S-methylglutathione formed by glutathione-S-transferase T1 in vitro. Arch Toxicol. 2001 Feb;74(12):760-7. The time-, protein-, and substrate-dependences of the enzymatic catalysis with the model substrates methyl bromide (MeBr) and methyl (MeCl) were studied. |
3(0,0,0,3) | Details |