| Name | thyroid stimulating hormone (protein family or complex) |
|---|---|
| Synonyms | Thyroid stimulating hormone |
| Name | pentachlorophenol |
|---|---|
| CAS | 2,3,4,5,6-pentachlorophenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19590699 | Dallaire R, Muckle G, Dewailly E, Jacobson SW, Jacobson JL, Sandanger TM, Sandau CD, Ayotte P: Thyroid hormone levels of pregnant inuit women and their infants exposed to environmental contaminants. Environ Health Perspect. 2009 Jun;117(6):1014-20. Epub 2009 Jan 29. METHODS: We measured thyroid hormone parameters [thyroid stimulating hormone (TSH), free (fT (4)), total (T (3)), thyroxine-binding globulin (TBG)] and concentrations of several contaminants [PCB-153, hydroxylated metabolites of PCBs (HO-PCBs), pentachlorophenol (PCP) and hexachlorobenzene (HCB)] in maternal plasma at delivery (n = 120), in umbilical cord plasma (n = 95), and in infant plasma at 7 months postpartum (n = 130). |
31(0,1,1,1) | Details |
| 10434936 | Beard AP, Bartlewski PM, Chandolia RK, Honaramooz A, Rawlings NC: Reproductive and endocrine function in rams exposed to the organochlorine pesticides lindane and pentachlorophenol from conception. J Reprod Fertil. 1999 Mar;115(2):303-14. Serum was collected every 2 weeks and at 27 weeks every 15 min for 6 h during both day and night, and for 1 h before and 5 h after stimulation with GnRH, adrenocorticotrophic hormone and thyroid-stimulating hormone. |
2(0,0,0,2) | Details |
| 8240387 | van Raaij JA, Frijters CM, van den Berg KJ: Hexachlorobenzene-induced hypothyroidism. Biochem Pharmacol. 1993 Oct 19;46(8):1385-91. The effects on thyroid hormone status were more pronounced after 4 weeks and also included increased thyroid stimulating hormone (TSH) levels. The major metabolite pentachlorophenol (PCP) also caused, by competitive interactions with thyroid hormone binding proteins in serum, a rapid and dose-dependent decrease of TT4 and FT4 levels, but not of TT3 levels in serum. |
1(0,0,0,1) | Details |
| 10632142 | Beard AP, Rawlings NC: Thyroid function and effects on reproduction in ewes exposed to the organochlorine pesticides lindane or pentachlorophenol (PCP) from conception. J Toxicol Environ Health A. 1999 Dec 24;58(8):509-30. Serum was collected every 2 wk. during development, daily during the synchronized cycle and frequently (every 15-60 min) for 6-18 h either with or without stimulation with thyroid-stimulating hormone (TSH) during the synchronized luteal phase or TSH/ (TRH) at 65-66 wk of age. |
1(0,0,0,1) | Details |
| 9923752 | Beard AP, Bartlewski PM, Rawlings NC: Endocrine and reproductive function in ewes exposed to the organochlorine pesticides lindane or pentachlorophenol. J Toxicol Environ Health A. 1999 Jan 8;56(1):23-46. After weaning, 6 ewes from each group were bled at 15-min intervals for 8 h during the day and night and for 1 h before and 5 h after i.v. administration of gonadotropin-releasing hormone, thyroid-stimulating hormone (TSH), and adrenocorticotropin, to measure serum concentrations of luteinizing hormone, follicle-stimulating hormone, (T4), and |
1(0,0,0,1) | Details |
| 19082768 | Kawaguchi M, Morohoshi K, Saita E, Yanagisawa R, Watanabe G, Takano H, Morita M, Imai H, Taya K, Himi T: Developmental exposure to pentachlorophenol affects the expression of thyroid hormone receptor beta1 and synapsin I in brain, resulting in thyroid function vulnerability in rats. Endocrine. 2008 Jun;33(3):277-84. Gene expressions of thyroid hormone receptor beta1 and synapsin I, factors that promote brain growth, was increased in the cerebral cortex of PCP-treated weanling females, whereas plasma concentrations of total were decreased in dams and weanling pups, and plasma thyroid-stimulating hormone concentrations were higher in PCP-treated weanling males. |
1(0,0,0,1) | Details |