| Name | ATPase |
|---|---|
| Synonyms | ATP7A; MK; ATPase; Cation transporting ATPase; ATP7A protein; ATPase Cu(2+) transporting alpha polypeptide; Copper pump 1; Copper transporting ATPase 1… |
| Name | pentachlorophenol |
|---|---|
| CAS | 2,3,4,5,6-pentachlorophenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2968120 | Arnold WM, Zimmermann U, Pauli W, Benzing M, Niehrs C, Ahlers J: The comparative influence of substituted phenols (especially chlorophenols) on yeast cells assayed by electro-rotation and other methods. Biochim Biophys Acta. 1988 Jul 7;942(1):83-95. Biochemical assays on 23 of the phenols showed that the rotational sensitivity runs closely parallel to the sensitivities of cell growth rate and of the plasmamembrane ATPase, but less closely to the inhibition of incorporation. Doses of 2.2 mumol/l of pentachlorophenol, or of 0.3 mumol/l of pentabromophenol were detectable after 3 h incubation at pH 4.0. |
1(0,0,0,1) | Details |
| 1447481 | Janik F, Wolf HU: The Ca (2+)-transport-ATPase of human erythrocytes as an in vitro toxicity test system--acute effects of some chlorinated compounds. J Appl Toxicol. 1992 Oct;12(5):351-8. Investigations to determine the inhibitory activity on the Ca (2+)-transport-ATPase of human erythrocyte membranes were performed with various compounds of toxicological significance, mostly chlorinated and mainly used as biocides, such as 4-chlorophenol, 2,6-dichlorophenol, 3,4-dichlorophenol, 2,3,4-trichlorophenol, 2,3,4,5-tetrachlorophenol, pentachlorophenol (PCP), captan, folpet, captafol, (+)-camphene, toxaphene, dichlorodiphenyltrichloroethane (DDT), lindane, endrin, dieldrin, alpha-endosulfan, beta-endosulfan, paraquat, diallate, 2,4-dichlorophenoxyacetic acid (2,4-D) and 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). |
34(0,1,1,4) | Details |
| 6460116 | Lorusso DJ, Miller TL, Deinzer ML: Effect of hydroxychlorodiphenyl ethers (chlorinated pre-and isopredioxins) on erythrocyte membrane adenosinetriphosphatase activity. J Toxicol Environ Health. 1981 Jul-Aug;8(1-2):215-23. Pure pentachlorophenol (PCP) caused both inhibition of Na+, K+, Mg2+-ATPase and stimulation of Mg2+-ATPase, although each effect required a higher concentration of PCP than was needed for the HO-CL9-DPEs. |
83(1,1,1,3) | Details |
| 6217194 | Ito M, Ohnishi Y, Itoh S, Nishimura M: Carbonyl -m-chlorophenyl hydrazone-resistant Escherichia coli mutant that exhibits a temperature-sensitive unc phenotype. J Bacteriol. 1983 Jan;153(1):310-5. Strain CM22 (ccr-2) was resistant to another uncoupler, pentachlorophenol, and to the inhibitors of -translocating ATPase, namely tributyltin and azide. |
81(1,1,1,1) | Details |
| 1647945 | Cascorbi I, Foret M: Interaction of xenobiotics on the -transport system and the Na+/K (+)-ATPase of human skin fibroblasts. Ecotoxicol Environ Saf. 1991 Feb;21(1):38-46. The combination of lipophilic with less lipophilic xenobiotics, such as pentachlorophenol with 4-chloroaniline, leads to additional effects. |
3(0,0,0,3) | Details |
| 6994811 | Ramos EH, de Bongioanni LC, Stoppani AO: Kinetics of L-[14C] transport in Saccharomyces cerevisiae: effect of energy coupling inhibitors. Biochim Biophys Acta. 1980 Jun 20;599(1):214-31. Dicyclohexylcarbodiimide, and diethylstilbestrol inhibit tranport at 0.05 mM L-[14C] in good agreement with a function of the plasmalemma ATPase for the operation of system 1. Dio-9, propionic and isobutyric acids, pentachlorophenol, carbonylcyanide 3-chlorophenylhydrazone and carbonylcyanide 4-trifluoromethoxyphenylhydrazone, which affect the gradient and/or the membrane potential inhibit L-[14C] uptake at all the assayed amino acid concentrations. 5. |
1(0,0,0,1) | Details |
| 19410655 | Dong YL, Zhou PJ, Jiang SY, Pan XW, Zhao XH: Induction of oxidative stress and apoptosis by pentachlorophenol in primary cultures of Carassius carassius hepatocytes. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Aug;150(2):179-85. Epub 2009 May 3. In addition, the induction of apoptosis by PCP was accompanied with Ca2+, Mg2+-ATPase activity decline, intracellular Ca2+ elevation, generation of intracellular reactive species (ROS), mitochondrial membrane potential (DeltaPsi (m)) disruption and ATP depletion. |
1(0,0,0,1) | Details |
| 6221918 | Hanke W, Gluth G, Bubel H, Muller R: Physiological changes in carps induced by pollution. Ecotoxicol Environ Saf. 1983 Apr;7(2):229-41. Several pollutants like DDT, atrazine, PCP, and others induce changes of and levels in serum, variations of the amount of liver and liver function, and exert changes of the activity of gill ATPase and acetylcholinesterase in brain and serum of carps. |
1(0,0,0,1) | Details |