| Name | succinate dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | Succinate dehydrogenase; Succinate dehydrogenases |
| Name | pentachlorophenol |
|---|---|
| CAS | 2,3,4,5,6-pentachlorophenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 508859 | Kostyrko VA, Iaguzhinskii LS: [Two sites of binding in mitochondrial oxidase] . Biokhimiia. 1979 Oct;44(10):1884-90. It was shown that the terminal part of the succinate dehydrogenase complex contains a site, which specifically binds the negatively charged phenols (e. g. pentachlorophenol, 2,4-dibromophenol, 2-methoxy-4,6-dibromophenol). |
33(0,1,1,3) | Details |
| 17215887 | Zhao Z, Rothery RA, Weiner JH: Effects of site-directed mutations in Escherichia coli succinate dehydrogenase on the enzyme activity and production of radicals. Biochem Cell Biol. 2006 Dec;84(6):1013-21. |
3(0,0,0,3) | Details |
| 3708023 | Afanas'eva EV, Kostyrko VA: [Pentachlorophenol inhibition of oxidation by the respiratory chain in submitochondrial particles from the bovine heart]. Biokhimiia. 1986 May;51(5):823-9. The identity of Ki values for PCP under these conditions suggests that the effect of PCP is due to the inhibitor interaction with the same component of the succinate dehydrogenase complex. |
2(0,0,0,2) | Details |
| 189227 | Burger A, Bellersheim M: Ca2+ -uptake into -storing granules of bovine splenic nerves. . Naunyn Schmiedebergs Arch Pharmacol. 1976 Dec;296(1):47-57. These particulate fractions were characterized by their content, succinate dehydrogenase and glucose-6-phosphatase activity. The behaviour of the 45 Ca2+ -uptake into all three fractions against varying ATP-concentrations, metabolic inhibitors (pentachlorophenol, desaspidine, 2,4-dinitrophenol, N-ethylmaleimide, p-chloromercuribenzoate, azide, amobarbital) and drugs (phenoxybenzamine, prenylamine, reserpine, bretylium, phentolamine) was studied. |
1(0,0,0,1) | Details |
| 7406888 | Cadenas E, Boveris A: Enhancement of peroxide formation by protophores and ionophores in antimycin-supplemented mitochondria. Biochem J. 1980 Apr 15;188(1):31-7. These rates are stimulated up to 13-fold by addition of protophores (carbonyl p-trifluoromethoxyphenylhydrazone, carbonyl m-chloromethoxyphenylhydrazone and pentachlorophenol). The effect of protophores, ionophores and Ca (2+) is analysed in relation to the propositions of a cyclic mechanism for the interaction of with succinate dehydrogenase and cytochromes b and c (1) [Wikstrom & Berden (1972) Biochim. |
1(0,0,0,1) | Details |
| 10486141 | Maklashina E, Cecchini G: Comparison of catalytic activity and inhibitors of reactions of succinate dehydrogenase - oxidoreductase) and reductase (Menaquinol- oxidoreductase) from Escherichia coli. Arch Biochem Biophys. 1999 Sep 15;369(2):223-32. A series of 2-alkyl-4,6-dinitrophenols and pentachlorophenol were found to be potent competitive inhibitors of both SQR and QFR. |
1(0,0,0,1) | Details |
| 3707947 | Choudhry ZM, Kotlyar AB, Vinogradov AD: Studies on the dehydrogenating system. Biochim Biophys Acta. 1986 Jun 10;850(1):131-8. In the diluted system the inactivation of the -depleted enzyme was completely prevented by the saturating concentrations of Q2, carboxin, thenoiltrifluoroacetone and pentachlorophenol, i.e., by the substrate and specific inhibitors of the enzyme. When the soluble reconstitutively active succinate dehydrogenase was treated with the reactivity of the enzyme towards low ferricyanide concentrations and its reconstitutive activity was significantly protected against aerobic inactivation. |
1(0,0,0,1) | Details |