| PubMed |
Abstract |
RScore(About this table) |
| 9347928 |
Radice S, Marabini L, Gervasoni M, Ferraris M, Chiesara E: Carbendazim and n-butylisocyanate: metabolites responsible for benomyl double action on cytochrome P450 in HepG2 cells. Toxicology. 1997 Nov 21;123(1-2):135-42.
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82(1,1,1,2) |
Details |
| 8607843 |
Rey-Grobellet X, Ferre N, Eeckhoutte C, Larrieu G, Pineau T, Galtier P: Structural requirements for the induction of cytochromes P450 by benzimidazole anthelmintic derivatives in cultured rabbit hepatocytes. Biochem Biophys Res Commun. 1996 Mar 27;220(3):789-94.
The effect of sulfur-containing benzimidazoles (thiabendazole, 5-hydroxy-thiabendazole, cambendazole) and sulfur-free derivatives (benzimidazole, carbendazim and 5-hydroxycarbendazim) on cytochrome P450 enzymes was investigated in primary cultures of rabbit hepatocytes considered 72 h after plating. |
81(1,1,1,1) |
Details |
| 20183062 |
Abass K, Turpeinen M, Pelkonen O: An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes. J Environ Sci Health B. 2009 Aug;44(6):553-63.
Some pesticides caused relatively potent inhibitions sporadically (carbendazim, CYP2D6, IC (50) = 12 micro M; atrazine, CYP3A4, IC (50) = 2.8 micro M; glyphosate, CYP2C9, IC (50) = 3.7 micro M; hexaflumuron, IC (50) = 6.0 micro M). |
1(0,0,0,1) |
Details |