| Name | endothelin 1 |
|---|---|
| Synonyms | EDN 1; EDN1; ET1; Endothelin 1; Endothelin 1 precursor; PPET 1; PPET1; Preproendothelin 1… |
| Name | diphenylamine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9706740 | Reddix RA, Mullet D, Fertel R, Cooke HJ: Endogenous inhibits endothelin-1-induced secretion in guinea pig colon. Nitric Oxide. 1998;2(1):28-36. The reduction in Isc in response to hemoglobin was reversed by and blockers of secretion, including bumetanide and diphenylamine-2-carboxylic acid, but not by the potassium channel blockers, barium and tetraethylammonium, nor by amiloride, an epithelial sodium channel blocker. |
2(0,0,0,2) | Details |
| 11369815 | Fortuno A, Muniz P, Zalba G, Fortuno MA, Diez J: The loop diuretic torasemide interferes with endothelin-1 actions in the aorta of hypertensive rats. Nephrol Dial Transplant. 2001;16 Suppl 1:18-21. The specific (Cl (-)) channel blocker diphenylamine-2-carboxylate inhibits both ET-1-induced responses in VSMCs (IC (50)=8.0+/-0.3x10 (-9) and 2.5+/-0.7x10 (-7) M, respectively). |
2(0,0,0,2) | Details |
| 10833531 | Phillips JE, Yeates DB: Bidirectional transepithelial water transport: -dependent mechanisms. J Membr Biol. 2000 Jun 1;175(3):213-21. Endothelin-1 induced a simultaneous increase in J (W)(B--> L) (7.0 to 7.7 microl/min/cm (2)) and decrease in J (W)(L--> B) (7.4 to 6.4 microl/min/cm (2)); and decreased the membrane resistance. Diphenylamine-2-carboxylate (DPC) reduced J (W)(B--> L) from 7.9 to 7. 3 microl/min/cm (2) and reduced the membrane potential difference by 38%. |
1(0,0,0,1) | Details |
| 9888876 | Suenobu N, Shichiri M, Iwashina M, Marumo F, Hirata Y: Natriuretic peptides and induce endothelial apoptosis via a -dependent mechanism. Arterioscler Thromb Vasc Biol. 1999 Jan;19(1):140-6. We studied whether endothelium-derived relaxing factor, (NO), and natriuretic peptides affect apoptosis of rat vascular endothelial cells via a -dependent pathway and whether such effects are antagonized by an endothelium-derived vasoconstrictor, endothelin-1 (ET-1). This dose-dependent relation was assessed by quantifying the fragmented and intact DNA contents by the diphenylamine method. |
1(0,0,0,1) | Details |