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Waters SL, Sarang SS, Wang KK, Schnellmann RG: Calpains mediate calcium and chloride influx during the late phase of cell injury. J Pharmacol Exp Ther. 1997 Dec;283(3):1177-84.
Finally, nifedipine, calpain inhibitor 1, PD150606 and the Cl- channel inhibitors [5-nitro-2-(3-phenylpropylamino)-benzoate, niflumic acid, diphenylamine-2-carboxylate, and indanyloxyacetic acid] blocked the increase in Cl- influx that occurs during the late phase of cell injury and triggers terminal cell swelling and death. |
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