| Name | NA K ATPase |
|---|---|
| Synonyms | (NA+ + K+)ATPase; ATP1A1; ATPase; ATPase Na+/K+ transporting alpha 1 polypeptide; Na (+) K (+) ATPase; Na (+),K (+) ATPase; Na + K + ATPase; Na K + ATPase… |
| Name | diphenylamine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8447429 | McBride RK, Stone KK, Marin MG: Oxidant injury alters barrier function of ferret tracheal epithelium. Am J Physiol. 1993 Feb;264(2 Pt 1):L165-74. Studies with amiloride, and diphenylamine-2-carboxylate are suggestive that oxidant stress transiently stimulates the Na-K-ATPase. |
81(1,1,1,1) | Details |
| 11207189 | Leung GP, Cheung KH, Tse CM, Wong PY: Na+ reabsorption in cultured rat epididymal epithelium via the Na+/nucleoside cotransporter. Biol Reprod. 2001 Mar;64(3):764-9. Moreover, the response was abolished by pretreatment of the tissue with ouabain, a Na+/K+-ATPase inhibitor, suggesting the involvement of Na+/nucleoside cotransporter on the apical side and Na+/K+-ATPase on the basolateral side in Na+ reabsorption. Addition of the Na+/K+/2Cl- symport inhibitor bumetanide to the basolateral side or the nonspecific Cl- channel blocker diphenylamine-2-carboxylate to the apical side showed no effect on the Isc response to excluding stimulation of Cl- secretion by as the cause of the -induced Isc. |
1(0,0,0,1) | Details |
| 2458457 | Bunce KT, Spraggs CF: Stimulation of electrogenic secretion by in guinea-pig isolated gastric mucosa. J Physiol. 1988 Jun;400:381-94. Both basal and -stimulated SCC were dependent on extracellular and inhibited by ouabain, indicating the importance of a gradient and the Na+-K+-ATPase in maintaining the electrogenic properties of the mucosa. 6. This interpretation was confirmed by the dependence of the basal SCC on extracellular and inhibition by the chloride channel blocker, diphenylamine-2-carboxylate. |
1(0,0,0,1) | Details |
| 8743460 | Sullivan LP, Grantham JJ: Mechanisms of fluid secretion by polycystic epithelia. Kidney Int. 1996 Jun;49(6):1586-91. Thus the functional Na,K-ATPase enzyme complex is located only in the basolateral membrane of the cystic cells and serves to maintain the transmembrane chemical and electrical gradients that drive anion secretion by other transport mechanisms. |
1(0,0,0,1) | Details |
| 8074243 | Al-Bazzaz FJ: Regulation of Na and Cl transport in sheep distal airways. Am J Physiol. 1994 Aug;267(2 Pt 1):L193-8. The data provide evidence for the presence in the sheep bronchiolar epithelium of active Na absorption that depends on a basolaterally located Na-K-ATPase ion pump. Exposure of the lumen to Cl channel blocker diphenylamine-2-carboxylate (1 mM) depolarized the bronchiole from a PD of 4.46 +/- 1.7 mV to 2.50 +/- 0.97 mV (n = 7, P < 0.03). |
1(0,0,0,1) | Details |
| 148466 | Costantino-Ceccarini E, Novikoff PM, Atkinson PH, Novikoff AB: Further characterization of HeLa S3 plasma membrane ghosts. J Cell Biol. 1978 May;77(2):448-63. Enrichment and recovery of fucosylglycoprotein parallel those for ouabain-sensitive Na+, K+-ATPase activity. Contamination by nuclei is 0.14%, too little for DNA detection by the diphenylamine reaction. |
1(0,0,0,1) | Details |
| 2466122 | Breuer W: Characterization of channels in membrane vesicles from the kidney outer medulla. J Membr Biol. 1989 Jan;107(1):35-42. The basolateral membrane of the thick ascending loop of Henle (TALH) of the mammalian kidney is highly enriched in Na+/K+ ATPase and has been shown by electrophysiological methods to be highly conductive to Cl-. Among the Cl- transport inhibitors tested, 5-nitro-2-(3-phenylpropylamino)- (NPPAB), 4,4'-diisothiocyano-stilbene-2,2'-disulfonate (DIDS), and diphenylamine-2-carboxylate (DPC) showed IC50 of 110, 200 and 550 microM, respectively. |
1(0,0,0,1) | Details |
| 8596713 | Cougnon M, Bouyer P, Hulin P, Anagnostopoulos T, Planelles G: Further investigation of ionic diffusive properties and of NH4+ pathways in Xenopus laevis oocyte cell membrane. Pflugers Arch. 1996 Feb;431(4):658-67. Diphenylamine-2-carboxylic acid (DPC), 3',5'-dichlorodiphenylamine-2-carboxylic acid (DCDPC) and gadolinium ions hyperpolarized Vm and increased Rm, suggesting the inhibition of nonselective cationic conductance (s). |
0(0,0,0,0) | Details |
| 8766016 | Poulsen JH, Machen TE: HCO3-dependent pHi regulation in tracheal epithelial cells. . Pflugers Arch. 1996 Jul;432(3):546-54. Cl-free solution and 500 microM H2DIDS (dihydro-4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid, blocks anion exchange and the outwardly rectifying Cl channel, ORCC), both blocked apparent anion exchange activity, but had no effect on the recovery; 100 microM DNDS (4-4''-dinitro-2-2'-stilbenedisulfonate blocks the ORCC but not the cystic fibrosis transmembrane conductance regulator, CFTR) had no effect on pHi recovery; DPC (diphenylamine carboxylate, blocks the CFTR and the ORCC) caused a complete and reversible inhibition of the recovery. |
0(0,0,0,0) | Details |