| Name | G protein |
|---|---|
| Synonyms | G gamma I; Guanine nucleotide binding protein 2; G protein; GNG 2; GNG2; GNGT 2; GNGT2; Guanine nucleotide binding protein gamma 2… |
| Name | diphenylamine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1375640 | Sun XP, Supplisson S, Torres R, Sachs G, Mayer E: Characterization of large-conductance channels in rabbit colonic smooth muscle. J Physiol. 1992 Mar;448:355-82. The stilbene derivative diiso-thiocyanato-stilbene-disulphonic acid (DIDS) and the diphenylamine-2-carboxylate analogue 5-nitro-2-(3-phenylpropylamino)- (NPPB) caused a dose-dependent, reversible flicker block of the small conductance and significantly reduced the macroscopic current flow through the channel. 6. In addition, the regulation of these channels by neurokinin-1 (NK-1) receptor agonists and G proteins was studied. 2. |
1(0,0,0,1) | Details |
| 7536699 | Inoue R: [Biophysical and pharmacological characterization of receptor-operated nonselective cation channels (ROCC) and their regulatory mechanisms in smooth muscle]. Nippon Yakurigaku Zasshi. 1995 Jan;105(1):11-22. The muscarinic receptor ROCC in guinea pig ileum (mROCC) have a unitary conductance of -25pS and are activated through a pertussis toxin-sensitive G protein. mROCC permeate Ca2+ and Ba2+ several fold more preferably than monovalent cations, and they are inhibited by various types of K channel blockers, diphenylamine-2-carboxylate derivatives and even by nicardipine and D-600 at high concentrations. mROCC are efficiently regulated by various physiological factors including the membrane potential, intracellular Ca2+ concentration, external pH and osmolarity. |
31(0,1,1,1) | Details |
| 1425983 | Tamaoki J, Chiyotani A, Takeyama K, Konno K: Effects of angiotensin II and angiotensin III on airway epithelial short-circuit current: involvement of pertussis toxin-sensitive G protein. Eur J Pharmacol. 1992 Sep 10;220(1):87-90. Both peptides increased the short-circuit current (Isc), an effect that was accompanied by the release of prostaglandin (PG) E2 and was abolished by indomethacin and diphenylamine-2-carboxylate but not by amiloride. |
2(0,0,0,2) | Details |