Protein Information

Name estrogen receptor
Synonyms ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA…

Compound Information

Name diphenylamine
CAS

Reference List

PubMed Abstract RScore(About this table)
18760603 Ohta K, Chiba Y, Ogawa T, Endo Y: Promising core structure for nuclear receptor ligands: design and synthesis of novel estrogen receptor ligands based on diphenylamine skeleton. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5050-3. Epub 2008 Aug 6.
162(2,2,2,2) Details
9730974 Gorodeski GI: Estrogen increases the permeability of the cultured human cervical epithelium by modulating cell deformability. Am J Physiol. 1998 Sep;275(3 Pt 1):C888-99.


Lowering luminal NaCl had no significant effect on RTE, and the Cl- channel blocker diphenylamine-2-carboxylate attenuated the hypertonicity-induced decrease in cell size to the same degree in control and estrogen-treated cells, suggesting estrogen effects on permeability and cell size are not mediated by modulating Na+ or Cl- transport.
0(0,0,0,0) Details