| Name | bradykinin |
|---|---|
| Synonyms | Alpha 2 thiol proteinase inhibitor; BDK; Bradykinin; KNG; KNG 1; KNG1; Kininogen; Kininogen 1 precursor… |
| Name | diphenylamine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10392553 | Furukawa M, Suzuki H, Ikeda K, Oshima T, Yamaya M, Sasaki H, Takasaka T: Kinin and stimulate Cl- secretion in gerbil middle ear epithelium: connection to otitis media. Hear Res. 1999 Jun;132(1-2):109-16. The effects of bradykinin (BK) and on transepithelial ion transport in primary cultures of gerbil middle ear epithelium were investigated. Diphenylamine-2-carboxylate or 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid, Cl- channel blockers, significantly blocked the I (sc) responses to lys-BK or |
2(0,0,0,2) | Details |
| 1767867 | Yamaya M, Finkbeiner WE, Widdicombe JH: Ion transport by cultures of human tracheobronchial submucosal glands. Am J Physiol. 1991 Dec;261(6 Pt 1):L485-90. The potency sequence for stimulation of Isc by mediators was methacholine greater than bradykinin greater than isoproterenol approximately or equal to Diphenylamine-2-carboxylic acid, however, had no effect on baseline Isc but markedly inhibited the Isc response to all mediators. |
2(0,0,0,2) | Details |
| 14715281 | Mahlangu DA, Dix JA: Halide fluxes in epithelial cells measured with an automated cell plate reader. Anal Biochem. 2004 Feb 1;325(1):28-34. Isoproterenol (a modulator of cAMP-activated channels) increased the exchange rate by a factor of 1.4+/-0.1; A23187 (a modulator of -activated channels) increased the rate by 3.4+/-0.4; bradykinin (also a modulator of -activated channels) increased the rate by 2.0+/-0.4; forskolin (a direct stimulator of adenylate cyclase) increased the rate by 2.7+/-0.3. Diphenylamine-2-carboxylate (a chloride channel blocker) decreased the rate by 0.12+/-0.03. |
1(0,0,0,1) | Details |
| 1319450 | Leung AY, Leung PY, Cheng-Chew SB, Wong PY: The role of calcitonin gene-related peptide in the regulation of anion secretion by the rat and human epididymis. J Endocrinol. 1992 May;133(2):259-68. The current could be inhibited by apical application of the chloride channel blocker, diphenylamine-2-carboxylate. In contrast to bradykinin, angiotensin II and endothelin I, the effect of CGRP was independent of prostaglandin synthesis. |
1(0,0,0,1) | Details |
| 2165124 | Wong PY, Fu WO, Huang SJ, Law WK: Effect of angiotensins on electrogenic anion transport in monolayer cultures of rat epididymis. J Endocrinol. 1990 Jun;125(3):449-56. The increase in SCC by AII was dependent upon extracellular Cl- and was inhibited by addition of a Cl- channel blocker, diphenylamine 2-carboxylate, to the apical surface. |
0(0,0,0,0) | Details |
| 1310213 | Verkman AS, Chao AC, Hartmann T: Hormonal regulation of Cl transport in polar airway epithelia measured by a fluorescent indicator. Am J Physiol. 1992 Jan;262(1 Pt 1):C23-31. Apical Cl transport was sensitive to diphenylamine-2-carboxylate (DPC) but not to whereas basolateral membrane Cl transport was sensitive to furosemide but not to DPC. |
0(0,0,0,0) | Details |