20121592 |
Baker OJ, Schulz DJ, Camden JM, Liao Z, Peterson TS, Seye CI, Petris MJ, Weisman GA: Rat Parotid Gland Cell Differentiation in Three-Dimensional Culture. Tissue Eng Part C Methods. 2010 Mar 8.
These 3D Par-C10 acinar-like spheres display characteristics similar to differentiated acini in salivary glands, including cell polarization, tight junction (TJ) formation required to maintain transepithelial potential difference, basolateral expression of aquaporin-3 and Na (+)/K (+)/2Cl (-) cotransporter-1, and responsiveness to the muscarinic receptor agonist carbachol that is decreased by the anion channel blocker diphenylamine-2-carboxylic acid or chloride replacement with gluconate. |
31(0,1,1,1) |
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