| Name | sphingomyelinase |
|---|---|
| Synonyms | CBP; CBP; Csk binding protein; PAG; PAG 1; PAG1; Phosphoprotein associated with glycosphingolipid enriched microdomains; Phosphoprotein associated with glycosphingolipid enriched microdomains 1… |
| Name | diphenylamine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19168702 | Noe J, Petrusca D, Rush N, Deng P, VanDemark M, Berdyshev E, Gu Y, Smith P, Schweitzer K, Pilewsky J, Natarajan V, Xu Z, Obukhov AG, Petrache I: CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis. Am J Respir Cell Mol Biol. 2009 Sep;41(3):314-23. Epub 2009 Jan 23. Both specific CFTR inhibition with 2-(phenylamino) diphenylamine-2-carboxylic acid, 5-[(4-carboxyphenyl) methylene]-2-thioxo-3-[(3-trifluoromethyl) phenyl-4-thi azolidinone (CFTR (inh)-172), or 5-nitro-2-(3-phenylpropylamino) and CFTR knockdown significantly attenuated endothelial cell apoptosis induced by staurosporine or H (2) O (2). Replenishing endogenous ceramides via sphingomyelinase supplementation restored the susceptibility of CFTR-inhibited lung endothelial cells to H (2) O (2)-induced apoptosis. |
1(0,0,0,1) | Details |
| 8757842 | Ngeleka M, Kwaga JK, White DG, Whittam TS, Riddell C, Goodhope R, Potter AA, Allan B: Escherichia coli cellulitis in broiler chickens: clonal relationships among strains and analysis of virulence-associated factors of isolates from diseased birds. Infect Immun. 1996 Aug;64(8):3118-26. The isolates were further characterized with respect to hemagglutination (HA); serum resistance; antibiotic susceptibility; production of colicin V, and hemolysin; expression of K1 or K5 capsule; sensitivity to cloacin DF13 after treatment with diphenylamine; expression of iron-regulated outer membrane proteins; and virulence in 1-day-old chickens. |
32(0,1,1,2) | Details |