Protein Information

Name Atrial natriuretic factor
Synonyms ANF; ANP; Atrial natriuretic factor; Atrial natriuretic factor precursor; Atrial natriuretic peptide; Atrial natriuretic polypeptide; Atrionatriureticfactor; Atriopeptin…

Compound Information

Name diphenylamine
CAS

Reference List

PubMed Abstract RScore(About this table)
2153599 Moriarty KJ, Higgs NB, Lees M, Tonge A, Wardle TD, Warhurst G: Influence of atrial natriuretic peptide on mammalian large intestine. . Gastroenterology. 1990 Mar;98(3):647-53.

The response to atrial natriuretic peptide was inhibited by (a) chloride-free solution on the serosal surface; (b) pretreatment of the tissues with the chloride channel blocker, diphenylamine-2-carboxylate (10 (-3) M mucosally); (c) pretreatment with d,l-verapamil (10 (-4) M mucosally and serosally); (d) calcium-free solution on the serosal surface; (e) pretreatment with tetrodotoxin (10 (-7) M to serosal surface); and (f) pretreatment with atropine (10 (-5) M serosally).
37(0,1,1,7) Details
7684181 Grotmol T, Rodnes JT, Buanes T, Christensen G, Landsverk T: Atrial natriuretic factor (ANF) does not affect ion transport in human intestine but does in porcine intestine. Acta Physiol Scand. 1993 Apr;147(4):417-29.

The aim of this study was to test whether atrial natriuretic factor (ANF) exerts any effect on human intestinal ion transport, and the porcine intestine was used as a positive control of ANF's effects.
The porcine Isc response was partly inhibited by chloride-free solution on the serosal side, by serosal application of bumetanide (10 (-4) M) and BaCl2 (10 (-3) M), and mucosal application of the chloride-channel blocker diphenylamine-2-carboxylate (DPC) (10 (-3) M).
1(0,0,0,1) Details
9888876 Suenobu N, Shichiri M, Iwashina M, Marumo F, Hirata Y: Natriuretic peptides and nitric oxide induce endothelial apoptosis via a cGMP-dependent mechanism. Arterioscler Thromb Vasc Biol. 1999 Jan;19(1):140-6.

Three natriuretic peptides (atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide) induced endothelial apoptosis as demonstrated by nucleosomal laddering on agarose gel electrophoresis and by the terminal deoxynucleotidyl transferase-mediated dUTP biotin nick end labeling method.
This dose-dependent relation was assessed by quantifying the fragmented and intact DNA contents by the diphenylamine method.
2(0,0,0,2) Details