| Name | acinus |
|---|---|
| Synonyms | ACIN 1; ACIN1; ACINUS; ACN; Apoptotic chromatin condensation inducer in the nucleus; apoptotic chromatin condensation inducer 1; apoptotic chromatin condensation inducer 1s |
| Name | allyl alcohol |
|---|---|
| CAS | 2-propen-1-ol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 669203 | Nostrant TT, Miller DL, Appelman HD, Gumucio JJ: Acinar distribution of liver cell regeneration after selective zonal injury in the rat. Gastroenterology. 1978 Aug;75(2):181-6. Liver cell regeneration after selective zonal injury induced by bromobenzene (acinar zone III damage) and allyl alcohol (acinar zone I damage) was examined in the context of the simple liver acinus. |
6(0,0,1,1) | Details |
| 10048720 | Werlich T, Stiller KJ, Machnik G: Experimental studies on the stem cell concept of liver regeneration. Exp Toxicol Pathol. 1999 Jan;51(1):93-8. In the present paper it will be demonstrated that under the condition of a simultaneous intoxication with allyl alcohol and tetrachlorcarbon a regenerative process occurs, which is composed of two distinct partial processes: 1. a "proliferative wave" of the persisting, non-necrotic differentiated hepatocytes of the acinus, starting at 24 h after intoxication and ending after > 48 h, and 2. a proliferation of cells at the rim of the portal fields, which afterwards enter the acinus and differentiate into hepatocytes, starting at 48 h after intoxication. |
6(0,0,1,1) | Details |
| 621433 | Gumucio JJ, Balabaud C, Miller DL, DeMason LJ, Appelman HD, Stoecker TJ, Franzblau DR: Bile secretion and liver cell heterogeneity in the rat. J Lab Clin Med. 1978 Feb;91(2):350-62. Changes in the removal of 14C-taurocholate from blood, in the biliary secretion of taurocholate, and in canalicular flow were determined after damage of the periportal (acinar zone 1) or centrilobular (acinar zone 3) areas by allyl alcohol or bromobenzene, respectively. Consequently, since the concentration of bile salts in sinusoidal blood at each zone determines the relative contribution of hepatocytes to bile salt transport, periportal cells probably transport the largest amount of bile salts reaching the acinus. |
1(0,0,0,1) | Details |
| 7905753 | Kress S, Katz N: Discrimination between periportal and pericentral necrosis of rat liver by determination of glutamine synthetase and other enzyme activities in serum. Eur J Clin Chem Clin Biochem. 1993 Nov;31(11):733-8. Periportal or pericentral necrosis of rat liver was produced by injection of allyl-alcohol or bromobenzene, respectively. Aspartate aminotransferase, which is more or less homogeneously distributed in the liver acinus, exhibited similar activities in serum after periportal and pericentral injury. |
1(0,0,0,1) | Details |