Protein Information

Name catalase
Synonyms CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases…

Compound Information

Name allyl alcohol
CAS 2-propen-1-ol

Reference List

PubMed Abstract RScore(About this table)
11306107 Moridani MY, Khan S, Chan T, Teng S, Beard K, O'Brien PJ: Cytochrome P450 2E1 metabolically activates propargyl alcohol: propiolaldehyde-induced hepatocyte cytotoxicity. Chem Biol Interact. 2001 Jan 30;130-132(1-3):931-42.

However, it is a poor substrate compared to allyl alcohol and it was therefore proposed that propargyl alcohol-induced liver injury involved metabolic activation by catalase/H (2) O (2) [E.G.
81(1,1,1,1) Details
8075374 DeMaster EG, Dahlseid T, Redfern B: Comparative oxidation of 2-propyn-1-ol with other low molecular weight unsaturated and saturated primary alcohols by bovine liver catalase in vitro. Chem Res Toxicol. 1994 May-Jun;7(3):414-9.

The oxidative metabolism of low molecular weight, saturated and unsaturated, primary alcohols, which include ethanol, allyl alcohol (2-propen-1-ol), and propargyl alcohol (2-propyn-1-ol), is generally accepted to occur via alcohol dehydrogenase; however, compared to other short-chain alcohols, 2-propyn-1-ol is a poor substrate for this enzyme.
3(0,0,0,3) Details
2732808 Ricci G, Chiaraluce R, Pitari G, Dupre S, Fujii O, Hosokawa Y, Yamaguchi K: Photooxidation of hypotaurine to taurine in the presence of flavins. J Nutr Sci Vitaminol. 1989 Apr;35(2):143-53.


The effectiveness of allyl alcohol as a scavenger pointed to a free-radical mechanism of the reaction.
0(0,0,0,0) Details
11565505 Kovelenov AIu, Lobzin IuV, Pluzhnikova NN, D'iachkov DG: [Effect of perftoran on experimental hepatitis] . Eksp Klin Farmakol. 2001 May-Jun;64(3):41-4.

The effect of perftoran on the course of experimental acute hepatitis in albino rats was studied on the hepatitis models induced by allyl alcohol or P. acnes culture with typhoid fever endotoxin.
The drug inhibits the activity of prooxidant enzymes (xanthine oxidase and myeloperoxidase of Kupffer cells) and induces the synthesis of factors accounting for the antiperoxidation protection in hepatocytes such as catalase, glucose-6-phosphate dehydrogenase, and reduced glutathione.
1(0,0,0,1) Details