Protein Information

Name xanthine oxidase
Synonyms XDH; XDHA; XO; XOD; XOR; Xanthene dehydrogenase; Xanthine dehydrogenase; Xanthine dehydrogenase/oxidase…

Compound Information

Name allyl alcohol
CAS 2-propen-1-ol

Reference List

PubMed Abstract RScore(About this table)
1897001 Brown PC, Thurman RG, Belinsky SA, Kauffman FC: Effect of allyl alcohol on xanthine dehydrogenase activity in the perfused rat liver. Toxicol Lett. 1991 Sep;58(1):1-6.

Since allyl alcohol injuries the liver by an oxygen-dependent mechanism, we examined the actions of this hepatotoxicant on the conversion of xanthine dehydrogenase into xanthine oxidase in perfused livers.
188(1,4,6,8) Details
11565505 Kovelenov AIu, Lobzin IuV, Pluzhnikova NN, D'iachkov DG: [Effect of perftoran on experimental hepatitis] . Eksp Klin Farmakol. 2001 May-Jun;64(3):41-4.

The effect of perftoran on the course of experimental acute hepatitis in albino rats was studied on the hepatitis models induced by allyl alcohol or P. acnes culture with typhoid fever endotoxin.
The drug inhibits the activity of prooxidant enzymes (xanthine oxidase and myeloperoxidase of Kupffer cells) and induces the synthesis of factors accounting for the antiperoxidation protection in hepatocytes such as catalase, glucose-6-phosphate dehydrogenase, and reduced glutathione.
1(0,0,0,1) Details